ArticleBMC plant biology2016
Several wall-associated kinases participate positively and negatively in basal defense against rice blast fungus.
Article in BMC plant biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers.
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110 citing papers in PubMed, 254 citations in OpenAlex.
- Role of cell wall-associated kinases in plant development and defense responses.Molecular biology reports · 2026Review
- Computational Predictions and Evolutionary Analysis ofInternational journal of molecular sciences · 2026Article
- ZmWAKL21 is a maize wall-associated kinase-like protein that interacts with AvrRppC and contributes to southern corn rust resistance.Cellular & molecular biology letters · 2026Article
- Dissecting multi-rust resistance in wheat through genome-wide association study, haplotype analysis, and marker validation.The plant genome · 2026Article
- GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- FScientific reports · 2025Article
- Screening for resistance to Pyrenophora graminea in hulless barley germplasm and subsequent morphological and transcriptomic analyses.BMC plant biology · 2025Article
- Investigating the Role of OsHDT701 and Other Blast-Associated Negative Regulatory Genes in Indica Rice Cultivar Ranjit Using Combined Wet Lab and Computational Approaches.Molecular biotechnology · 2025Article
- Research Progress on Rice-Blast-Resistance-Related Genes.Plants (Basel, Switzerland) · 2025Review
- TaWAKL8-2B, a wall-associated receptor-like kinase, mediates wheat rust resistance by linalool and ROS accumulation.Stress biology · 2025Article
- Transcriptional Dynamics of Receptor-Based Genes Reveal Immunity Hubs in Rice Response toInternational journal of molecular sciences · 2025Article
- Coordinated transcriptomic and metabolomic responses in rice reveal lignin-based physical barriers as key mechanisms of nonhost resistance to rust fungi.PLoS genetics · 2025Article
- One stone for multiple birds: PigmR integrates multiple defense pathways for high and broad-spectrum blast resistance in rice.Stress biology · 2025Article
- Comparative transcriptome and genome analysis between susceptible Zhefang rice variety Diantun 502 and its resistance variety Diantun 506 upon Magnaporthe oryzae infection.BMC plant biology · 2025Article
- Transcriptomic analysis of rice cultivars with distinct resistance mechanisms toFrontiers in plant science · 2025Article
- A new bacterial blight resistance geneFrontiers in plant science · 2025Article
- Article
- Identification of significant SNPs and candidate loci for blast disease resistance via GWAS and population structure analysis in ARC panel ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2024Article
- Review
- Comparative Field Evaluation and Transcriptome Analysis Reveals that Chromosome Doubling Enhances Sheath Blight Resistance in Rice.Rice (New York, N.Y.) · 2024Article
50 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundReceptor-like kinases are well-known to play key roles in disease resistance. Among them, the Wall-associated kinases (WAKs) have been shown to be positive regulators of fungal disease resistance in several plant species. WAK genes are often transcriptionally regulated during infection but the pathways involved in this regulation are not known. In rice, the OsWAK gene family is significantly amplified compared to Arabidopsis. The possibility that several WAKs participate in different ways to basal defense has not been addressed. Moreover, the direct requirement of rice OSWAK genes in regulating defense has not been explored.
resultsHere we show using rice (Oryza sativa) loss-of-function mutants of four selected OsWAK genes, that individual OsWAKs are required for quantitative resistance to the rice blast fungus, Magnaporthe oryzae. While OsWAK14, OsWAK91 and OsWAK92 positively regulate quantitative resistance, OsWAK112d is a negative regulator of blast resistance. In addition, we show that the very early transcriptional regulation of the rice OsWAK genes is triggered by chitin and is partially under the control of the chitin receptor CEBiP. Finally, we show that OsWAK91 is required for H2O2 production and sufficient to enhance defense gene expression during infection.
conclusionsWe conclude that the rice OsWAK genes studied are part of basal defense response, potentially mediated by chitin from fungal cell walls. This work also shows that some OsWAKs, like OsWAK112d, may act as negative regulators of disease resistance.
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