Evidence map›Paper›PMID 26772192›Full record

ArticleClinical journal of the American Society of Nephrology : CJASN2016

Effect of Synbiotic Therapy on Gut-Derived Uremic Toxins and the Intestinal Microbiome in Patients with CKD.

Nosratola D Vaziri

2 registry-linked trialsAbstract readEditorialComment
In one paragraph

Article in Clinical journal of the American Society of Nephrology : CJASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04204005 nacompletednot on this mapstarted 2017, after this paper: background citation

Probiotics-addicted Low-protein Diet for Microbiota Modulation in Patients With Advanced Chronic Kidney Disease (ProLowCKD): a Protocol of Placebo-controlled Randomized Trial

TypeinterventionalSponsorProbiotical S.p.A.Ran2017 to 2020Enrolled50ConditionsRenal Failure ChronicArmsProbiotics
NCT07443280 narecruitingnot on this mapstarted 2026, after this paper: background citation

Alterations of Gut Derived Uremic Toxins and Microbiome Metabolites by Multispecies Synbiotic Supplementation in Hemodialysis Patients

TypeinterventionalSponsorTungs' Taichung Metroharbour HospitalRan2026 to 2026Enrolled30ConditionsSymbiotic, Uremic Toxins, Gut -MicrobiotaArmsMultispecies Synbiotic Supplementation
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  15. Kidney-gut crosstalk in renal disease.Irish journal of medical science · 2021
    Review
  16. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Nosratola D VaziriDivision of Nephrology and Hypertension, University of California, Irvine, California ndvaziri@uci.edu.

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
NCATS NIH HHS UL1 TR001414
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gastrointestinal MicrobiomeSynbioticsHumansRenal Insufficiency, ChronicUremiabiologicalchronic kidney diseasegastrointestinal microbiomehumansintestineoxidative stresspathophysiology of renal disease and progressionsynbioticstoxins

Identifiers

PMID26772192
PMCPMC4741052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.