Evidence map›Paper›PMID 26771637›Full record

SynthesisNutrients2016

Effect of Oat β-Glucan Intake on Glycaemic Control and Insulin Sensitivity of Diabetic Patients: A Meta-Analysis of Randomized Controlled Trials.

Xiao Li Shen, Tao Zhao, Yuanzhong Zhou, Xiuquan Shi, Yan Zou, Guohua Zhao

2 registry-linked trialsOpen access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Nutrients, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 34 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 6 pooled it
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03569501 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Influence of DHA/Oat on Maternal and Neonatal Metabolic Health in Gestational Diabetes Mellitus

TypeinterventionalSponsorXinhua Hospital, Shanghai Jiao Tong University School of MedicineRan2017 to 2019Enrolled80ConditionsGestational Diabetes Mellitus in PregnancyArmsDHA, oat grains
NCT04299763 phase2completednot on this mapstarted 2018, after this paper: background citation

Oat β-glucans as a Supplement in Chilean Subjects With Type 2 Diabetes for Metabolic Control

TypeinterventionalSponsorCentro de Estudios en Alimentación y Nutrición, ChileRan2018 to 2019Enrolled37ConditionsType2 DiabetesArmsOat Beta-glucan as a Supplement in Type 2 Diabetics
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 6 syntheses or guidelines pooled it, 91 citations in OpenAlex.

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  17. [Nutrition for diabetic patients (Update 2023)].Wiener klinische Wochenschrift · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiao Li ShenSchool of Public Health, Zunyi Medical University, Zunyi 563000, Guizhou, China. xiaolishen1983@163.com.
Tao ZhaoSchool of Public Health, Zunyi Medical University, Zunyi 563000, Guizhou, China. 15186613384@163.com.
Yuanzhong ZhouSchool of Public Health, Zunyi Medical University, Zunyi 563000, Guizhou, China. zhouyuanzhong@163.com.
Xiuquan ShiSchool of Public Health, Zunyi Medical University, Zunyi 563000, Guizhou, China. xqshi@zmc.edu.cn.
Yan ZouSchool of Public Health, Zunyi Medical University, Zunyi 563000, Guizhou, China. zouyan54321@126.com.
Guohua ZhaoCollege of Food Science, Southwest University, Chongqing 400716, China. zhaogh@swu.edu.cn.
Zunyi Medical University · CNSouthwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many individual studies on oat β-glucan (OBG) confirmed its functionality in improving type 2 diabetes mellitus (T2DM), but disagreements were identified among those results. To derive a pooled estimate of these results, relevant articles, published before 5 September 2015, were collected from four electronic databases (Pubmed, Cochrane Library, Scopus, and Web of Science) and subjected to meta-analysis in the present work. In total, four articles, dealing with 350 T2DM patients combined, met the inclusion criteria. Compared to control, T2DM patients administrated OBG from 2.5 to 3.5 g/day for 3 to 8 weeks presented significantly lowered concentrations in fasting plasma glucose (FPG) by -0.52 (95% CI: -0.94, -0.10) mmol/L (p = 0.01) and glycosylated hemoglobin (HbA1c) by -0.21% (95% CI: -0.40, -0.02) (p = 0.03). However, OBG intake did not significantly lower the fasting plasma insulin (FPI) concentration. In conclusion, mediate-term OBG intake (3-8 weeks) favored the glycaemic control of T2DM patients but did not improve their insulin sensitivity. Regrettably, data upon the effects of long-term OBG intake on glycaemic control and insulin sensitivity were scarce, which is of much importance and should be addressed in future research.

Indexed as

Insulin ResistanceAdultAgedbeta-GlucansBlood GlucoseDiabetes Mellitus, Type 2FastingFemaleGlycated HemoglobinHumansInsulinMaleMiddle AgedRandomized Controlled Trials as Topicbeta-glucan, (1-3)(1-4)-beta-GlucansBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanInsulindiabetes mellitusglycaemic controlinsulin sensitivitymeta-analysisoat β-glucan

Identifiers

PMID26771637
PMCPMC4728652
OpenAlexW2238262427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.