ArticleMarine drugs2016
Five New Cytotoxic Metabolites from the Marine Fungus Neosartorya pseudofischeri.
Article in Marine drugs, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 41 citations in OpenAlex.
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- Chemical Constituents and Anticancer Activities of Marine-Derived FungusMolecules (Basel, Switzerland) · 2024Article
- Chemical Constituents and Bioactivities of the Plant-Derived FungusMolecules (Basel, Switzerland) · 2024Article
- Secondary Metabolites from the Coral-Derived FungusMarine drugs · 2023Article
- Soil-BorneInternational journal of molecular sciences · 2023Review
- Bioactive Compounds from Terrestrial and Marine-Derived Fungi of the GenusMolecules (Basel, Switzerland) · 2022Review
- Biosynthesis of Terpenoid-Pyrrolobenzoxazine Hybrid Natural Product CJ-12662.Angewandte Chemie (International ed. in English) · 2022Article
- A New Fungal Triterpene from the FungusMarine drugs · 2022Article
- New Drimane Sesquiterpenes and Polyketides from Marine-Derived FungusMarine drugs · 2021Article
- A Review of Terpenes from Marine-Derived Fungi: 2015-2019.Marine drugs · 2020Review
- Chemical Diversity and Biological Activities of Meroterpenoids from Marine Derived-Fungi: A Comprehensive Update.Marine drugs · 2020Review
- Hybrid Polyketides from aMarine drugs · 2019Article
- Synthesis and insecticidal efficacy of pyripyropene derivatives. Part II-Invention of afidopyropen.The Journal of antibiotics · 2019Article
- Aplysinopsin-type and Bromotyrosine-derived Alkaloids from the South China Sea Sponge Fascaplysinopsis reticulata.Scientific reports · 2019Article
- Studies on the Chemical Diversities of Secondary Metabolites Produced byMolecules (Basel, Switzerland) · 2018Article
- Soil Bacteria Isolated From Tunisian Arid Areas Show Promising Antimicrobial Activities Against Gram-Negatives.Frontiers in microbiology · 2018Article
- Labradorins with Antibacterial Activity Produced by Pseudomonas sp.Molecules (Basel, Switzerland) · 2017Article
- A new species of Trichoderma hypoxylon harbours abundant secondary metabolites.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The marine fungus Neosartorya pseudofischeri was isolated from Acanthaster planci from the South China Sea. In a preliminary bioactivity screening, the crude methanol extract of the fungal mycelia showed significant inhibitory activity against the Sf9 cell line from the fall armyworm Spodoptera frugiperda. Five novel compounds, including 5-olefin phenylpyropene A (1), 13-dehydroxylpyripyropene A (4), deacetylsesquiterpene (7), 5-formyl-6-hydroxy-8-isopropyl-2- naphthoic acid (9) and 6,8-dihydroxy-3-((1E,3E)-penta-1,3-dien-1-yl)isochroman-1-one (10), together with eleven known compounds, phenylpyropene A (2) and C (3), pyripyropene A (5), 7-deacetylpyripyropene A (6), (1S,2R,4aR,5R,8R,8aR)-1,8a-dihydroxy-2-acetoxy-3,8-dimethyl-5- (prop-1-en-2-yl)-1,2,4a, 5,6,7,8,8a-octahydronaphthalene (8), isochaetominine C (11), trichodermamide A (12), indolyl-3-acetic acid methyl ester (13), 1-acetyl-β-carboline (14), 1,2,3,4-tetrahydro-6-hydroxyl-2-methyl-l,3,4-trioxopyrazino[l,2-a]-indole (15) and fumiquinazoline F (16), were obtained. The structures of these compounds were determined mainly by MS and NMR data. The absolute configuration of 9 was assigned by the single-crystal X-ray diffraction studies. Compounds 1-11 and 15 showed significant cytotoxicity against the Sf9 cells from S. frugiperda.
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