ArticlePloS one2016
Calculating Stress: From Entropy to a Thermodynamic Concept of Health and Disease.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 27 citations in OpenAlex.
- Real-time measurement of entropy production and export in humans: A step toward entropically informed medicine.Annals of the New York Academy of Sciences · 2025Article
- Stress management in family environment.Indian journal of psychiatry · 2024Article
- Continuous Monitoring of Entropy Production and Entropy Flow in Humans Exercising under Heat Stress.Entropy (Basel, Switzerland) · 2023Article
- Homeostatic model of human thermoregulation with bi-stability.Scientific reports · 2021Article
- The Applicability of the Poincaré Plot in the Analysis of Variability of Reaction Time during Serial Testing.International journal of environmental research and public health · 2021Observational
- Health and Disease Are Dynamic Complex-Adaptive States Implications for Practice and Research.Frontiers in psychiatry · 2021Article
- Stress entropic load: New stress measurement method?PloS one · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To date, contemporary science has lacked a satisfactory tool for the objective expression of stress. This text thus introduces a new-thermodynamically derived-approach to stress measurement, based on entropy production in time and independent of the quality or modality of a given stressor or a combination thereof. Hereto, we propose a novel model of stress response based on thermodynamic modelling of entropy production, both in the tissues/organs and in regulatory feedbacks. Stress response is expressed in our model on the basis of stress entropic load (SEL), a variable we introduced previously; the mathematical expression of SEL, provided here for the first time, now allows us to describe the various states of a living system, including differentiating between states of health and disease. The resulting calculation of stress response regardless of the type of stressor(s) in question is thus poised to become an entirely new tool for predicting the development of a living system.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.