ArticleOrganic letters2016
Oxyboration with and without a Catalyst: Borylated Isoxazoles via B-O σ-Bond Addition.
Article in Organic letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Metal-Free Electrophilic Borylative Cyclizations of Alkynes.Chemical record (New York, N.Y.) · 2026Review
- Electrochemical assembly of isoxazolesChemical science · 2024Article
- Novel Synthesis of Dihydroisoxazoles byMolecules (Basel, Switzerland) · 2023Article
- Lewis acid-promoted direct synthesis of isoxazole derivatives.Beilstein journal of organic chemistry · 2023Article
- Green multicomponent synthesis, antimicrobial and antioxidant evaluation of novel 5-amino-isoxazole-4-carbonitriles.Chemistry Central journal · 2018Article
- Selective oxymetalation of terminal alkynesChemical science · 2018Article
- Catalyst-Free Formal Thioboration to Synthesize Borylated Benzothiophenes and Dihydrothiophenes.Angewandte Chemie (International ed. in English) · 2016Article
- Kinetic Study of Carbophilic Lewis Acid Catalyzed Oxyboration and the Noninnocent Role of Sodium Chloride.Organometallics · 2016Article
- Catalyst-Free Synthesis of Borylated Lactones from Esters via Electrophilic Oxyboration.Journal of the American Chemical Society · 2016Article
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3 authors.
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Abstract
Herein we report an oxyboration reaction with activated substrates that employs B-O σ bond additions to C-C π bonds to form borylated isoxazoles, which are potential building blocks for drug discovery. Although this reaction can be effectively catalyzed by gold, it is the first example of uncatalyzed oxyboration of C-C π bonds by B-O σ bonds--and only the second example that is catalyzed. This oxyboration reaction is tolerant of groups incompatible with alternative lithiation/borylation and palladium-catalyzed C-H activation/borylation technologies for the synthesis of borylated isoxazoles.
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