ArticlePloS one2016
Co-Circulation of Canine Coronavirus I and IIa/b with High Prevalence and Genetic Diversity in Heilongjiang Province, Northeast China.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review and meta-analysis of canine enteric coronavirus prevalence in dogs of mainland China.Virology journal · 2024Pooled it
- Genetic and Evolutionary Analysis of Canine Coronavirus in Guangxi Province, China, for 2021-2024.Veterinary sciences · 2024Article
- Pathological Effects of SARS-CoV-2 Associated with Hematological Abnormalities.Current issues in molecular biology · 2023Review
- A One Health Perspective on Canine Coronavirus: A Wolf in Sheep's Clothing?Microorganisms · 2023Review
- Epidemiology and Molecular Characterizations of Coronavirus from Companion Animals Living in Chengdu, Southwest China.Transboundary and emerging diseases · 2023Article
- Genetic characterization and evolutionary analysis of canine parvovirus in Tangshan, China.Archives of virology · 2022Article
- Detection and Molecular Characterization of Canine Alphacoronavirus in Free-Roaming Dogs, Bangladesh.Viruses · 2021Article
- Molecular characterization of the FCoV-like canine coronavirus HLJ-071 in China.BMC veterinary research · 2021Article
- Establishment of an indirect ELISA-based method involving the use of a multiepitope recombinant S protein to detect antibodies against canine coronavirus.Archives of virology · 2021Article
- Evolution, Interspecies Transmission, and Zoonotic Significance of Animal Coronaviruses.Frontiers in veterinary science · 2021Review
- Development of a nanoparticle-assisted PCR assay to distinguish canine coronaviruses I and II.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021Article
- Drawing Comparisons between SARS-CoV-2 and the Animal Coronaviruses.Microorganisms · 2020Review
- Epidemiological and phylogenetic analysis of canine kobuviruses in Tangshan, China.Archives of virology · 2020Article
- Coronavirus Infections in Companion Animals: Virology, Epidemiology, Clinical and Pathologic Features.Viruses · 2020Review
- Etiology and genetic evolution of canine coronavirus circulating in five provinces of China, during 2018-2019.Microbial pathogenesis · 2020Article
- Molecular diversity ofHeliyon · 2020Article
- A Mini-Review on the Epidemiology of Canine Parvovirus in China.Frontiers in veterinary science · 2020Review
- Molecular characterization of HLJ-073, a recombinant canine coronavirus strain from China with an ORF3abc deletion.Archives of virology · 2019Article
- A multiplex PCR method for the simultaneous detection of three viruses associated with canine viral enteric infections.Archives of virology · 2018Article
- Molecular surveillance of canine distemper virus in diarrhoetic puppies in northeast China from May 2014 to April 2015.The Journal of veterinary medical science · 2018Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To trace the evolution of canine coronavirus (CCoV), 201 stool samples from diarrheic dogs in northeast China were subjected to reverse transcription-polymerase chain reactions (RT-PCRs) targeting the partial M and S genes of CCoV, followed by an epidemiological analysis. M gene RT-PCRs showed that 28.36% (57/201) of the samples were positive for CCoV; of the 57 positive samples, CCoV-I and CCoV-II accounted for 15.79% (9/57) and 84.21% (48/57), respectively. A sequence comparison of the partial M gene revealed nucleotide homologies of 88.4%-100% among the 57 CCoV strains, and 88.7%-96.2% identity between the 57 CCoV strains and the Chinese reference strain HF3. The CCoV-I and CCoV-II strains exhibited genetic diversity when compared with reference strains from China and other countries. The 57 CCoV strains exhibited high co-infection rates with canine kobuvirus (CaKV) (33.33%) and canine parvovirus-2 (CPV-2) (31.58%). The CCoV prevalence in diarrheic dogs differed significantly with immunization status, regions, seasons, and ages. Moreover, 28 S genes were amplified from the 57 CCoV-positive samples, including 26 CCoV-IIa strains, one CCoV-IIb strain, and one CCoV-I strain. A sequence comparison of the partial S gene revealed 86.3%-100% nucleotide identity among the 26 CCoV-IIa strains, and 89.6%-92.2% identity between the 26 CCoV-IIa strains and the Chinese reference strain V1. The 26 CCoV-IIa strains showed genetic diversity when compared with reference strains from China and other countries. Our data provide evidence that CCoV-I, CCoV-IIa, and CCoV-IIb strains co-circulate in the diarrhoetic dogs in northeast China, high co-infection rates with CaKV and CPV-2 were observed, and the CCoV-II strains exhibited high prevalence and genetic diversity.
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