ArticlePloS one2016
Transient Tear Film Dysfunction after Cataract Surgery in Diabetic Patients.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
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Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Bridging the gap in managing dry eye disease: a consensus report by the Taiwan society of cataract and refractive surgeons.BMC ophthalmology · 2024Guideline
- Dry Eye and Phacoemulsification Cataract Surgery: A Systematic Review and Meta-Analysis.Frontiers in medicine · 2021Pooled it
- Effects of Preservative-free 3% Diquafosol in Patients with Pre-existing Dry Eye Disease after Cataract Surgery: A Randomized Clinical Trial.Scientific reports · 2019Trial
- Preoperative Risk Factors for Dry Eye Symptoms After Cataract Surgery: Femtosecond Laser-Assisted Cataract Surgery (FLACS) Versus Standard Cataract Surgery (SCS).Journal of clinical medicine · 2025Article
- Ocular surface changes and corneal epithelial remodeling after cataract surgery in patients with type 2 diabetes: a case-control study.BMC ophthalmology · 2025Article
- Tissue Damage on Ocular Surface After Combined Phacoemulsification with Limbal Relaxing Incision Compared with Standard Phacoemulsification.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Review
- Ocular surface parameter changes in the untreated fellow eye after unilateral cataract surgery with short-term administration of anti-inflammatory eye drops.Scientific reports · 2024Article
- Tear film dysfunction after clear corneal phacoemulsification in diabetics and non-diabetics.Indian journal of ophthalmology · 2023Article
- Tear inflammation related indexes after cataract surgery in elderly patients with type 2 diabetes mellitus.World journal of clinical cases · 2023Article
- Alpha-Glycerylphosphorylcholine and D-Panthenol Eye Drops in Patients Undergoing Cataract Surgery.Journal of ophthalmology · 2022Article
- Upper Eyelid Meibomian Gland Dysfunction is a Risk Factor for Dry Eye Symptoms Following Cataract Surgery in the Early Phase.Clinical ophthalmology (Auckland, N.Z.) · 2022Article
- Cataract Surgery Considerations for Diabetic Patients.Current diabetes reports · 2021Review
- Effects of cataract surgery on symptoms and findings of dry eye in subjects with and without preexisting dry eye.Japanese journal of ophthalmology · 2020Article
- Dry Eye Disease after Cataract Surgery: Study of its Determinants and Risk FactorsTurkish journal of ophthalmology · 2020Observational
- Changes in ocular surface status after phacoemulsification in patients with senile cataract.International ophthalmology · 2019Article
- Diabetes and Phacoemulsification Cataract Surgery: Difficulties, Risks and Potential Complications.Journal of clinical medicine · 2019Review
- Impact of 0.1% sodium hyaluronate and 0.2% sodium hyaluronate artificial tears on postoperative discomfort following cataract extraction surgery: a comparative study.Eye and vision (London, England) · 2019Article
- Influence of diabetes mellitus on anterior segment of the eye.Clinical interventions in aging · 2019Review
- Hydroxypropyl methylcellulose 2% for dry eye prevention during phacoemulsification in senile and diabetic patients.International ophthalmology · 2018Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDiabetes mellitus is an increasingly common systemic disease. Many diabetic patients seek cataract surgery for a better visual acuity. Unlike in the general population, the influence of cataract surgery on tear film function in diabetic patients remains elusive. The aim of this study was to evaluate the tear function in diabetic and nondiabetic patients following cataract surgery.
methodsIn this prospective, interventional case series, 174 diabetic patients without dry eye syndrome (DES) and 474 age-matched nondiabetic patients as control who underwent phacoemulsification were enrolled at two different eye centers between January 2011 and January 2013. Patients were followed up at baseline and at 7 days, 1 month, and 3 months postoperatively. Ocular symptom scores (Ocular Surface Disease Index, OSDI) and tear film function including tear film stability (tear film break-up time, TBUT), corneal epithelium integrity (corneal fluorescein staining, CFS), and tear secretion (Schirmer's I test, SIT) were evaluated.
resultsIn total, 83.9% of the diabetic patients (146 cases with 185 eyes) and 89.0% of the nondiabetic patients (422 cases with 463 eyes) completed all check-ups after the interventions (P = 0.095). The incidence of DES was 17.1% in the diabetic patients and 8.1% in the nondiabetic patients at 7 days after cataract surgery. In the diabetic patients, the incidence of DES remained 4.8% at 1 month postoperatively and decreased to zero at 3 months after surgery. No DES was diagnosed in nondiabetic patients at either the 1-month or 3-month follow-up. Compared with the baseline, the diabetic patients had worse symptom scores and lower TBUT values at 7 days and 1 month but not at 3 months postoperatively. In the nondiabetic patients, symptom scores and TBUT values had returned to preoperative levels at 1-month check-up. CFS scores and SIT values did not change significantly postoperatively in either group (P = 0.916 and P = 0.964, respectively).
conclusionsDiabetic patients undergoing cataract surgery are prone to DES. Ocular symptoms and tear film stability are transiently worsened in diabetic patients and are restored more slowly than those in nondiabetic patients.
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