Evidence map›Paper›PMID 26770887›Full record

ArticleJournal of developmental biology

Pbx4 is Required for the Temporal Onset of Zebrafish Myocardial Differentiation.

Robert M Kao, Joel G Rurik, Gist H Farr, Xiu Rong Dong, Mark W Majesky, Lisa Maves

Open access · goldAbstract read
In one paragraph

Article in Journal of developmental biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Zebrafish as a New Tool in Heart Preservation Research.Journal of cardiovascular development and disease · 2021
    Review
  6. Article
  7. Article
  8. Functional testing of a humanDisease models & mechanisms · 2018
    Article
  9. Atrazine exposure elicits copy number alterations in the zebrafish genome.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2017
    Article
  10. Hox Genes in Cardiovascular Development and Diseases.Journal of developmental biology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Robert M KaoCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, 1900 9th Avenue, Seattle, WA 98101, USA.
Joel G RurikCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, 1900 9th Avenue, Seattle, WA 98101, USA.
Gist H FarrCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, 1900 9th Avenue, Seattle, WA 98101, USA.
Xiu Rong DongCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, 1900 9th Avenue, Seattle, WA 98101, USA.
Mark W MajeskyCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, 1900 9th Avenue, Seattle, WA 98101, USA; Division of Cardiology, Department of Pediatrics, University of Washington, Seattle, WA 98105, USA.
Lisa MavesCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, 1900 9th Avenue, Seattle, WA 98101, USA; Division of Cardiology, Department of Pediatrics, University of Washington, Seattle, WA 98105, USA.
Seattle Children's Hospital · USUniversity of Washington · US

Funding

Resident Progenitor Cells in the AdventitiaR01HL123650 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI MAJESKY, MARK W. · 2014 to 2017
$2.4M
NHLBI NIH HHS R01 HL123650
6 · The paper itself

Abstract

Proper control of the temporal onset of cellular differentiation is critical for regulating cell lineage decisions and morphogenesis during development. Pbx homeodomain transcription factors have emerged as important regulators of cellular differentiation. We previously showed, by using antisense morpholino knockdown, that Pbx factors are needed for the timely activation of myocardial differentiation in zebrafish. In order to gain further insight into the roles of Pbx factors in heart development, we show here that zebrafish

Indexed as

cardiomyocytedifferentiationmyocardial morphogenesisoutflow tractpbx4proepicardiumzebrafish

Identifiers

PMID26770887
PMCPMC4709844
OpenAlexW2103762536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.