ArticleVirus evolution2015
Time dependence of evolutionary metrics during the 2009 pandemic influenza virus outbreak.
Article in Virus evolution, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Concepts and methods for predicting viral evolution.bioRxiv : the preprint server for biology · 2024Article
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- Inferring enterovirus D68 transmission dynamics from the genomic data of two 2022 North American outbreaks.Npj viruses · 2024Article
- An atlas of continuous adaptive evolution in endemic human viruses.Cell host & microbe · 2023Article
- Article
- The evolution of SARS-CoV-2.Nature reviews. Microbiology · 2023Review
- Purifying Selection Determines the Short-Term Time Dependency of Evolutionary Rates in SARS-CoV-2 and pH1N1 Influenza.Molecular biology and evolution · 2022Article
- Contributions of adaptation and purifying selection to SARS-CoV-2 evolution.Virus evolution · 2022Article
- Genomic epidemiology of the first epidemic wave of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Palestine.Microbial genomics · 2021Article
- Substantial Antigenic Drift in the Hemagglutinin Protein of Swine Influenza A Viruses.Viruses · 2020Article
- Article
- The Evolutionary History and Spatiotemporal Dynamics of the NC Lineage of Citrus Tristeza Virus.Viruses · 2017Article
- The substitution rate of HIV-1 subtypes: a genomic approach.Virus evolution · 2017Article
- A Comparison of One-Rate and Two-Rate Inference Frameworks for Site-Specific dN/dS Estimation.Genetics · 2016Article
- Zika virus in the Americas: Early epidemiological and genetic findings.Science (New York, N.Y.) · 2016Article
- Causes of evolutionary rate variation among protein sites.Nature reviews. Genetics · 2016Review
- The utility of protein structure as a predictor of site-wise dN/dS varies widely among HIV-1 proteins.Journal of the Royal Society, Interface · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
With the expansion of DNA sequencing technology, quantifying evolution in emerging viral outbreaks has become an important tool for scientists and public health officials. Although it is known that the degree of sequence divergence significantly affects the calculation of evolutionary metrics in viral outbreaks, the extent and duration of this effect during an actual outbreak remains unclear. We have analyzed how limited divergence time during an early viral outbreak affects the accuracy of molecular evolutionary metrics. Using sequence data from the first 25 months of the 2009 pandemic H1N1 (pH1N1) outbreak, we calculated each of three different standard evolutionary metrics-molecular clock rate (i.e., evolutionary rate), whole gene
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.