Evidence map›Paper›PMID 26770625›Full record

ArticleInternational journal of clinical and experimental medicine2015

Long-term disease control in a refractory multiple myeloma patient treated with bortezomib mono-therapy: a case report and review of literature.

Gaixiang Xu, Min Yang, Wenbin Qian

Open access · greenAbstract readCase Reports
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gaixiang XuDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou Zhejiang, China.
Min YangDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou Zhejiang, China.
Wenbin QianDepartment of Hematology, The First Affiliated Hospital, College of Medicine, Zhejiang University Hangzhou Zhejiang, China.
Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) accounts for 1.5% of all cancers and approximately 13% of all hematologic malignancies. Therapy for MM has substantially improved after the application of immunomodulatory drugs and proteasome inhibitors. The first proteasome inhibitor, bortezomib, can be considered a major milestone in treatment of MM, greatly improving the response rates and overall survival in front-line and relapsed/refractory settings. However, the prognosis of patients with progressive disease remains poor. In this article, we report a case of refractory MM patient who gained a long time disease control by bortezomib mono-therapy and do a critical review of the literature. We aim to share our experience of efficiency and safety of the long term mono-therapy of bortezomib in a refractory MM.

Indexed as

bortezomibMultiple myelomaproteasome inhibitor

Identifiers

PMID26770625
PMCPMC4694525
OpenAlexW2271290142

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.