ArticleInternational journal of clinical and experimental medicine2015
The use of vancomycin in the treatment of adult patients with methicillin-resistant Staphylococcus aureus (MRSA) infection: a survey in a tertiary hospital in China.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Drug-Drug Interactions in Nosocomial Infections: An Updated Review for Clinicians.Pharmaceutics · 2024Review
- Approaches to Septic Arthritis of the Knee Post Anterior Cruciate Ligament Reconstruction.Current reviews in musculoskeletal medicine · 2023Review
- Epidemiology ofAntibiotics (Basel, Switzerland) · 2023Review
- Contamination and Antimicrobial Susceptibility Testing ofVeterinary medicine international · 2021Article
- Characterization of the anti-Staphylococcus aureus fraction from Penthorum chinense Pursh stems.BMC complementary and alternative medicine · 2019Article
- Recent advances inInfection and drug resistance · 2019Review
- Rapid diagnostic test and use of antibiotic against methicillin-resistant Staphylococcus aureus in adult intensive care unit.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVancomycin is frequently used in the treatment of methicillin-resistant Staphylococcus aureus (MRSA).
objectivesTo determine MRSA infection status and the use of vancomycin in its treatment at a teaching hospital in China.
methodsWe retrospectively reviewed 140 cases of MRSA infection that were treated from January 2013 to October 2014. We analyzed the etiology of MRSA infection and the use of vancomycin in these cases.
resultsMRSA infection mainly occurred in elderly patients concomitant with a variety of diseases, which incidence was more in men than women. More cases of MRSA infection were encountered in the ICU than in other departments. The positive culture results for MRSA were obtained in the sputum (38.57%), pharyngeal swab (19.29%), blood (5.71%), and wound secretion (11.43%) samples. The MRSA patients were sensitive to vancomycin, with the minimum inhibitory concentration (MIC) being 1 μg/mL in 53.80% of the cases and 2 μg/mL in 44.10% of the cases, respectively. Among the 35 (25%) cases treated with vancomycin, 23 were cured, while 3 died and 7 (20%) were considered as an unreasonable application.
conclusionsMRSA infection mainly appeared in patients admitted to the ICU. The MIC of vancomycin had a tendency to increase gradually.
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Identifiers
26770588PMC4694488What OpenQuestion holds
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