Evidence map›Paper›PMID 26770571›Full record

ArticleInternational journal of clinical and experimental medicine2015

Does aggressive and expectant management of severe preeclampsia affect the neurologic development of the infant?

Arif Aktuğ Ertekin, Bilge Kapudere, Meryem Kurek Eken, Gülşah İlhan, Şükriye Dırman, Mehmet Akif Sargın, Engin Deniz, Güner Karatekin, Ebru Çöğendez, Murat Api

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Expectant Versus Interventionist Care in the Management of Severe Preeclampsia Remote from Term: A Systematic Review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2021
    Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Arif Aktuğ ErtekinFaculty of Health Sciences-Istanbul, Uskudar University Turkey.
Bilge KapudereDepartment of Obstetrics and Gynaecology-Istanbul, Zeynep Kamil Women and Children Diseases, Education and Research Hospital Turkey.
Meryem Kurek EkenDepartment of Obstetrics and Gynaecology-Istanbul, Zeynep Kamil Women and Children Diseases, Education and Research Hospital Turkey.
Gülşah İlhanDepartment of Obstetrics and Gynaecology-Istanbul, Suleymaniye Research and Educational Hospital Turkey.
Şükriye DırmanDepartment of Child Development-Istanbul, Zeynep Kamil Women and Children Diseases, Education and Research Hospital Turkey.
Mehmet Akif SargınDepartment of Obstetrics and Gynaecology-Istanbul, Fatih Sultan Mehmet Research and Educational Hospital Turkey.
Engin DenizDepartment of Pediatric Neurology-Istanbul, Zeynep Kamil Women and Children Diseases, Education and Research Hospital Turkey.
Güner KaratekinDepartment of Child Development-Istanbul, Zeynep Kamil Women and Children Diseases, Education and Research Hospital Turkey.
Ebru ÇöğendezDepartment of Obstetrics and Gynaecology-Istanbul, Zeynep Kamil Women and Children Diseases, Education and Research Hospital Turkey.
Murat ApiDepartment of Obstetrics and Gynaecology-Istanbul, Zeynep Kamil Women and Children Diseases, Education and Research Hospital Turkey.
Zeynep Kamil Hospital · TRFatih Sultan Mehmet Eğitim Ve Araştırma Hastanesi · TRİstanbul Kanuni Sultan Süleyman Eğitim ve Araştırma Hastanesi · TRÜsküdar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare and evaluate the influences of expectant and aggressive management of severe preeclampsia on the first year neurologic development of the infants in pregnancies between 27 and 34 weeks of pregnancy.

methodsSeventy women with severe preeclampsia between 27 and 34 weeks of gestation were included in the study. 37 patients were managed aggressively (Group 1) and 33 patients were managed expectantly (Group 2). Glucocorticoids, magnesium sulfate infusion and antihypertensive drugs were administered to each group. After glucocorticoid administration was completed Group 1 was delivered either by cesarean section or vaginal delivery. In Group 2 magnesium sulfate infusion was stopped after glucocorticoid administration was completed. Antihypertensive drugs were given, bed rest and intensive fetal monitorization were continued in this group.

resultsThe average weeks of gestation, one minute and five minute apgar scores and hospitalization time in intensive care unit were similar in both groups (P > 0.05). Three neonatal complications in Group 2 and five in Group 1 were detected according to the Denver Developmental Screening Test-II and one pathologic case was detected in both groups following neurologic examination. Neonatal mortality was seen in seven patients in Group 1 and one in Group 2. There were no significant differences between groups in terms of neonatal mortality and morbidity and maternal morbidity (P > 0.05). The average latency period was 3.45 ± 5.48 days in Group 2 and none in Group 1.

conclusionThere was no significant difference in the first year neurological development of infants whose mothers underwent either expectant and aggressive management for severe preeclampsia.

Indexed as

aggressive managementexpectant managementneurologic developmentSevere preeclampsia

Identifiers

PMID26770571
PMCPMC4694471
OpenAlexW2405066918

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.