Evidence map›Paper›PMID 26770550›Full record

ArticleInternational journal of clinical and experimental medicine2015

Observations on the curative effect of lactulose for postpartum constipation based on a large sample study.

Yu Zhou, Xinghua Yang, Ling Fan, Yuanfang Zhu, Yurong Jiang, Zhen Li, Guoping Xiong, Jingxin Shen, Zhihong Su, Ping Wu and 2 more

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. [Seoul Consensus on Clinical Practice Guidelines for Functional Constipation].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Guideline
  2. Pharmacologic Treatment of Chronic Constipation.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 11 institutions in 1 country.

Yu ZhouDepartment of Obstetrics, Shandong Province Hospital Jinan 250014, Shandong, China.
Xinghua YangSchool of Public Health, Capital Medical University Beijing 100069, China.
Ling FanDepartment of Obstetrics, Beijing Gynaecology and Obstetrics Hospital of Capital Medical University Beijing 100069, China.
Yuanfang ZhuDepartment of Obstetrics, The First Affiliated Hospital of Nanchang University Nanchang 330006, Jiangxi, China.
Yurong JiangDepartment of Obstetrics, Maternal and Child Health Hospital of Hunan Province Changsha 410008, Hunan, China.
Zhen LiDepartment of Obstetrics, Xinqiao Hospital Chongqing 400037, Sichuan, China.
Guoping XiongDepartment of Obstetrics, Wuhan Central Hospital Wuhan 430014, Hubei, China.
Jingxin ShenDepartment of Obstetrics, The Third Xiangya Hospital of Central-South University Changsha 410013, Hunan, China.
Zhihong SuDepartment of Obstetrics, Lanzhou General Hospital of Chinese People's Liberation Army Lanzhou 730050, Gansu, China.
Ping WuDepartment of Obstetrics, Chongqing Three Gorges Central Hospital Chongqing 404000, China.
Danrui WangDepartment of Obstetrics, The Second Affiliated Hospital of Xinjiang Medical University Urumqi, Xinjiang 830028, China.
Xietong WangDepartment of Obstetrics, Shandong Province Hospital Jinan 250014, Shandong, China.
Second Hospital of Shandong University · CNBeijing Obstetrics and Gynecology Hospital · CNCapital Medical University · CNCentral Hospital of Wuhan · CNCentral South University · CNChongqing Three Gorges Central Hospital · CNHunan Provincial Maternal and Child Health Hospital · CNLanzhou Army General Hospital · CNNanchang University · CNXinjiang Medical University · CNXinqiao Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledTo evaluate the efficacy and safety of lactulose in the intervention treatment of postpartum women with constipation.

methodsThe study adopted the multicenter clinical survey with a big sample which enrolled 4781 valid questionnaires from postpartum women in 18 different districts. All of them were treated with lactulose oral solution. Their constipation-related symptoms and routine examination on blood, urine and stool were monitored before and after lactulose intervention. The treatment duration lasted 2 weeks and all the patients were followed for 4 weeks.

resultTheir stool consistency, daily defecation frequencies, defecating time and dyschezia were improved significantly after lactulose intervention, and the good therapeutic effect was remained at the off-medication session. Furthermore, abnormal rate of each index in blood, urine and stool examination showed a decreased trend.

conclusionLactulose offered good therapeutic benefit and could be developed as an effective intervention to postpartum women with constipation.

Indexed as

constipationlactulosePostpartum

Identifiers

PMID26770550
PMCPMC4694450
OpenAlexW2242136720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.