ArticleInternational journal of clinical and experimental medicine2015
The prevalence of hyperprolactinemia in non-functioning pituitary macroadenomas.
Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Article
- Resolution of Hyperprolactinemia Caused by Pituitary Stalk Compression After Transsphenoidal Surgery for Pituitary Tumors.Brain tumor research and treatment · 2025Article
- A new and useful tool for differentiating prolactinomas from non-functioning pituitary adenomas: a pilot study of the cabergoline disconnection test.Einstein (Sao Paulo, Brazil) · 2025Article
- Article
- Article
- Speed of response to dopaminergic agents in prolactinomas.Endocrine · 2022Article
- Tumor volume improves preoperative differentiation of prolactinomas and nonfunctioning pituitary adenomas.Endocrine · 2021Article
- The prevalence of freezing of gait in Parkinson's disease and in patients with different disease durations and severities.Chinese neurosurgical journal · 2020Article
- Epidemiology, clinical presentation and diagnosis of non-functioning pituitary adenomas.Pituitary · 2018Review
- Effects of pterostilbene on treating hyperprolactinemia and related mechanisms.American journal of translational research · 2016Article
- Co-occurrence of Functional Gonadotroph Adenoma and Lactotroph Adenoma: A Case Report and Literature Review.AACE clinical case reportsArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe prevalence of hyperprolactinemia in non-functioning pituitary macroadenomas (NFPMAs) is not well known, and hyperprolactinemia caused by a NFPMA is currently associated with diagnostic uncertainty. Thus, the aim of this study was to evaluate the prevalence of hyperprolactinemia in NFPMAs.
methodsA meta-analysis of all existing articles in PubMed was conducted. The search string was designed as "(non-functioning pituitary tumor OR non-functioning pituitary tumor OR non-functioning pituitary macroadenomas OR non-functioning pituitary macroadenomas OR non-functioning pituitary adenomas OR non-functioning pituitary adenomas) and hyperprolactinemia". References of the articles found were also reviewed. Study selection and data extraction were performed independently by two reviewers. Data were analyzed with STATA 11.0 software (StataCorp LP, USA). The fixed effects model was used to evaluate these studies.
resultsThe search identified 57 published studies, seven of which were accepted for the final meta-analysis. The authors found an overall estimated 40.2% prevalence of (95% CI, 36.6%-43.7%) hyperprolactinemia in NFPMAs.
conclusionsGiven the high frequency of hyperprolactinemia in NFPMAs, a diagnosis of NFPMA or prolactinoma should be made more carefully.
Indexed as
Identifiers
26770524PMC4694424W2410925400What OpenQuestion holds
Registered trials
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