Evidence map›Paper›PMID 26770482›Full record

ArticleInternational journal of clinical and experimental medicine2015

A new characterization for nonarteritic anterior ischemic optic neuropathy.

Aipeng Li, Lin Li, Miyang Li, Xiaoru Shi

Abstract read
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Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Aipeng LiDapertment of Ophthalmology, First Hospital of Jilin University Changchun 130021, Jilin, China.
Lin LiDepartment of Ophthalmology, China-Japan Union Hospital of Jilin University Changchun 130033, Jilin, China.
Miyang LiDepartment of Clinical Laboratory, China-Japan Union Hospital of Jilin University Changchun 130033, Jilin, China.
Xiaoru ShiDapertment of Ophthalmology, First Hospital of Jilin University Changchun 130021, Jilin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is to investigate the clinical characteristics of patients with nonarteritic anterior ischemic optic neuropathy (NAION). Totally 133 patients (156 eyes) were included in this study. At the first visit and follow-up visits, the patients were subjected to the ophthalmic evaluations, including the fundus photography, visual field (VF) test, fluorescein fundus angiography, and optical coherence tomography (OCT). The visual acuity (VA) of 156 eyes and the VF of 148 eyes were evaluated. For the VA assessment, 59 (38%), 67 (43%), and 30 (19%) cases presented with an initial VA ≥ 20/40, between 20/40 and 20/400, and ≤ 20/400, respectively. VA was improved in 44% and deteriorated in 8% of the patients with VA < 20/20 after NAION onset. Inferior or superior altitudinal defects, constricted fields, and nasal steps were the most common VF defects. In the eyes with VF defects, 32 cases (22%) were improved, and 25 cases (17%) were worsened. In the 61 cases (39%) with VA ≤ 20/200 at NAION onset, neuroepithelial detachment in the fovea was found in 37 eyes (61%). For the optic disc assessment, retinal nerve fiber layer (RNFL) thickening was the most common symptom of NAION. Out of the 36 eyes with ONA or DR, 72% showed VA improvement after the NAION occurrence in the contralateral eye. Poor microcirculation perfusion in the bilateral optic nerve hypoplasia (ONH) might be the underlying mechanism for NAION, which could be relieved by compromising the blood supply to the one side.

Indexed as

Nonarteritic anterior ischemic optic neuropathyoptical coherence tomographyshort posterior ciliary arteries

Identifiers

PMID26770482
PMCPMC4694382

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.