Evidence map›Paper›PMID 26770426›Full record

ArticleInternational journal of clinical and experimental medicine2015

Sarcopenia as a prognostic factor in hepatolithiasis-associated intrahepatic cholangiocarcinoma patients following hepatectomy: a retrospective study.

Gongting Zhou, Haili Bao, Qiqiang Zeng, Weijian Hu, Qiyu Zhang

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Article in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 6 of them syntheses that pooled it.

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12citing papers in PubMed, 6 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  12. Low skeletal muscle mass as predictor of postoperative complications and decreased overall survival in locally advanced head and neck squamous cell carcinoma: the role of ultrasound of rectus femoris muscle.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Gongting ZhouSchool of Medicine, Wenzhou Medical University Wenzhou, Zhejiang, China.
Haili BaoSchool of Medicine, Wenzhou Medical University Wenzhou, Zhejiang, China.
Qiqiang ZengThe First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.
Weijian HuSchool of Medicine, Wenzhou Medical University Wenzhou, Zhejiang, China.
Qiyu ZhangThe First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSarcopenia is closely associated with poor performance status and high mortality in cancer patients. The present study is to determine the correlation between sarcopenia and prognosis of hepatectomy for hepatolithiasis-associated intrahepatic cholangiocarcinoma (IHHCC).

methodsSixty-seven eligible IHHCC patients who underwent hepatectomy, between January 2000 and August 2014 were retrospectively evaluated. Sarcopenia was determined from skeletal muscle index (SMI), assessed by skeletal muscle mass on axial computed tomography images. Factors contributing to overall survival (OS) and recurrence-free survival (RFS) were analyzed by univariate and multivariate analyses.

resultsSarcopenia occurred in 33 (49.3%) out of 67 patients. Median OS of the enrolled patients was 12 months. Sarcopenic patients had a shorter OS compared with non-sarcopenic patients (P < 0.001). On univariate analyses, sarcopenia was significantly associated with overall survival (OS) and recurrence-free survival (RFS; both P < 0.05). On multivariate analysis, sarcopenic patients suffered poor overall survival (P < 0.001) and recurrence-free survival (P = 0.011) compared with non-sarcopenic patients.

conclusionsPreoperative sarcopenia is an independent biomarker of poor prognosis in IHHCC patients following hepatectomy. The identification of sarcopenia may enhance a clinical consideration on decision making for IHHCC patients before surgery.

Indexed as

hepatectomyhepatolithiasis-associated intrahepatic cholangiocarcinoma (IHHCC)prognosisSarcopenia

Identifiers

PMID26770426
PMCPMC4694326

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