Evidence map›Paper›PMID 26770303›Full record

ReviewInternational journal of clinical and experimental medicine2015

Stem cells as cellular vehicles for gene therapy against glioblastoma.

Wei Wang, Fanlong Liu, Bingyu Xiang, Charlie Xiang, Xiaozhou Mou

Abstract readReview
In one paragraph

Review in International journal of clinical and experimental medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei WangClinical Research Institute, Zhejiang Provincial People's HospitalHangzhou 310014, China; Department of Orthopaedics, The Second Affiliated Hospital, School of Medicine, Zhejiang UniversityHangzhou 310009, China.
Fanlong LiuDepartment of Anus, Rectum & Colon Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University Hangzhou 310003, China.
Bingyu XiangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University Hangzhou 310003, China.
Charlie XiangState Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University Hangzhou 310003, China.
Xiaozhou MouClinical Research Institute, Zhejiang Provincial People's Hospital Hangzhou 310014, China.

Funding

Analysis: Emotion-Based Alcohol Consumption with fMRI and Experimental ParadigmK01AA020102 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI CYDERS, MELISSA A · 2011 to 2015
$770k
NIAAA NIH HHS K01 AA020102
6 · The paper itself

Abstract

Glioblastoma (GBM) is the most common and deadliest primary tumor in adults, with current treatments having limited specific and efficient delivery of therapeutic drugs to tumor sites or cells. Therefore, the development of alternative treatment options is urgently needed. Stem cells are considered as ideal cellular vehicles for gene therapy against glioblastoma. In this paper, we reviewed the recent studies investigating the use of different types of stem cells as cellular vehicles and the gene of interests against the glioblastoma, as well as the future directions of the application of cellular vehicles mediated therapy for glioblastoma.

Indexed as

cellular vehiclegene therapyGliomastem cell

Identifiers

PMID26770303
PMCPMC4694203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.