Research Battles: Survival Tips From a Veteran.

Linda L Isaacs

Abstract read

In one paragraph

Article in Integrative medicine (Encinitas, Calif.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Pancreatic Proteolytic Enzymes and Cancer: New Support for an Old Theory.Integrative cancer therapies
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Linda L Isaacsgraduated with a undergraduate degree in biochemistry, with high distinction, from the University of Kentucky. She went on to receive her medical degree from Vanderbilt University School of Medicine in 1985. She completed a residency in internal medicine at the Department of Veteran's Affairs Medical Center at New York University Medical School, and she is board certified in internal medicine. Since 1985, Dr Isaacs had researched with Nicholas Gonzalez, md , until his untimely passing this year. She currently practices internal medicine in New York, New York.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies of nonorthodox medical treatments may go awry because of inherent flaws in designs that are better suited for trials of pharmaceutical products. Unintended consequences may follow from efforts at randomization, the lack of lead-in periods, required visits for medical assessment, inadequate screening, and a lack of trial publicity. A veteran of a mismanaged trial shares her experiences.

Identifiers

PMID26770164

PMCPMC4712871

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.