ReviewIntegrative medicine (Encinitas, Calif.)2014
Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology.
Review in Integrative medicine (Encinitas, Calif.), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Application of Metabolomics in the Exploration of Bioactive Compounds and Drug Development from Medicinal Fungi.Metabolites · 2026Review
- Synergistic apoptotic and epithelial-mesenchymal transition-inhibitory effects ofVeterinary world · 2026Article
- Effect of Agaricus bisporus Stalk Replacement of Soybean on Productive Performance, Egg Quality and Intestinal Microbiota of Laying Hens.Veterinary medicine and science · 2025Article
- The Assessment of Mercury Concentrations in Two Species of Edible Forest Mushrooms,Foods (Basel, Switzerland) · 2025Article
- Wild Mushrooms as a Source of Bioactive Compounds and Their Antioxidant Properties-Preliminary Studies.Foods (Basel, Switzerland) · 2024Article
- Medicinal Mushrooms in Metastatic Breast Cancer: What Is Their Therapeutic Potential as Adjuvant in Clinical Settings?Current issues in molecular biology · 2024Review
- Mushroom consumption and cardiometabolic health outcomes in the general population: a systematic review.Nutrition research and practice · 2024Review
- Unlocking the Power: New Insights into the Anti-Aging Properties of Mushrooms.Journal of fungi (Basel, Switzerland) · 2024Review
- Immunomodulatory Effects of Modified Colostrum, Whey, and Their Combination With Other Natural Products: Effects on Natural Killer Cells.Current therapeutic research, clinical and experimental · 2024Article
- Common foods for boosting human immunity: A review.Food science & nutrition · 2023Review
- Cordycepin (3'dA) Induces Cell Death of AC133Cancers · 2023Article
- Mushroom-Based Supplements in Italy: Let's Open Pandora's Box.Nutrients · 2023Article
- Review
- Immunostimulatory Effect of Postbiotics Prepared fromPharmaceuticals (Basel, Switzerland) · 2022Article
- Review
- Immune-Enhancing Effect of Submerged Culture ofInternational journal of molecular sciences · 2022Article
- GC-MS Analysis of Potentially Volatile Compounds ofFrontiers in microbiology · 2022Article
- Improved Survival and Quality of Life Through an Integrative, Multidisciplinary Oncological Approach: Pathophysiological Analysis of Four Clinical Cancer Cases and Review of the Literature.Frontiers in pharmacology · 2022Article
- Fungal Mushrooms: A Natural Compound With Therapeutic Applications.Frontiers in pharmacology · 2022Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review discusses the immunological roles of 5 major mushrooms in oncology: Agaricus blazei, Cordyceps sinensis, Grifola frondosa, Ganoderma lucidum, and Trametes versicolor. These mushrooms were selected based on the body of research performed on mushroom immunology in an oncology model. First, this article focuses on how mushrooms modify cytokines within specific cancer models and on how those cytokines affect the disease process. Second, this article examines the direct effect of mushrooms on cancer. Finally, this article presents an analysis of how mushrooms interact with chemotherapeutic agents, including their effects on its efficacy and on the myelosuppression that results from it. For these 5 mushrooms, an abundance of in vitro evidence exists that elucidates the anticancer immunological mechanisms. Preliminary research in humans is also available and is promising for treatment.
Identifiers
26770080PMC4684115What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.