ArticleBMJ open2016
Association between toothbrushing and risk factors for cardiovascular disease: a large-scale, cross-sectional Japanese study.
Article in BMJ open, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Impact of Oral Hygiene Practices in Reducing Cardiometabolic Risk, Incidence, and Mortality: A Systematic Review.International journal of environmental research and public health · 2024Pooled it
- Meta-analysis on the association between the frequency of tooth brushing and hypertension risk.Journal of clinical hypertension (Greenwich, Conn.) · 2022Pooled it
- Association between toothbrushing habits and hypertension in the general population.Scientific reports · 2025Article
- Association of tooth brushing behavior with risks of major chronic health outcomes: a scoping review.BMC oral health · 2025Article
- Oral Hygiene Practices and Glucose Profiles Assessed Through Continuous Glucose Monitoring in Adults With Type 2 Diabetes.Diabetes spectrum : a publication of the American Diabetes Association · 2025Article
- Screening for Systemic Diseases Associated with Dental Self-Care in Japanese Adolescents.Journal of clinical medicine · 2024Article
- Association between oral health behavior and chronic diseases among middle-aged and older adults in Beijing, China.BMC oral health · 2023Article
- A Scoping Review of the Relation Between Toothbrushing and Diabetes Knowledge, Glycemic Control, and Oral Health Outcomes in People With Type 2 Diabetes.Diabetes spectrum : a publication of the American Diabetes Association · 2023Article
- Article
- Associations of oral hygiene with incident hypertension and type 2 diabetes mellitus: A population based cohort study in Southwest China.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Association between Frequency of Toothbrushing and Metabolic Syndrome among Adolescents: A 5-Year Follow-Up Study.International journal of environmental research and public health · 2022Article
- Frequency of tooth brushing as a predictive factor for future kidney function decline.Journal of nephrology · 2022Article
- Associations of toothbrushing behaviour with risks of vascular and nonvascular diseases in Chinese adults.European journal of clinical investigation · 2021Article
- Health Behaviors and Self-Reported Oral Health among Centenarians in Nanjing, China: A Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- A Correlation Study of the Microbiota Between Oral Cavity and Tonsils in Children With Tonsillar Hypertrophy.Frontiers in cellular and infection microbiology · 2021Article
- The Optimal Range of Serum Uric Acid for Cardiometabolic Diseases: A 5-Year Japanese Cohort Study.Journal of clinical medicine · 2020Article
- Article
- Association Between Toothbrushing and Behavioral Risk Factors of Non-communicable Diseases: A population Based Survey of 4500 adults in China.Scientific reports · 2019Article
- High rate of calories from protein is associated with higher prevalence of hypertension.Journal of human hypertension · 2019Article
- The oral health status, behaviours and knowledge of patients with cardiovascular disease in Sydney Australia: a cross-sectional survey.BMC oral health · 2019Article
Corrections and comments
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Authors and funding
10 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo clarify the association between toothbrushing and risk factors for cardiovascular disease--namely, hypertension (HT), diabetes mellitus (DM), dyslipidaemia (DL), hyperuricaemia (HUA) and chronic kidney disease (CKD).
designA large-scale, single-centre, cross-sectional study.
settingSt Luke's International Hospital, Center for Preventive Medicine, Tokyo, Japan, between January 2004 and June 2010.
participantsThis study examined the toothbrushing practices of 85,866 individuals according to the 3-category frequency criterion: 'after every meal', 'at least once a day' and 'less than once a day'. The ORs by frequency were calculated for the prevalences of HT, DM, DL, HUA and CKD according to binominal logistic regression analyses adjusted for age, gender, body mass index and lifestyle habits--smoking, drinking, walk time and sleep time.
resultsThe prevalences of the risk factors were as follows: HT ('after every meal': 13.3%, 'at least once a day': 17.9% and 'less than once a day': 31.0%), DM (3.1%, 5.3% and 17.4%, respectively), DL (29.0%, 42.1% and 60.3%, respectively), HUA (8.6%, 17.5% and 27.2%, respectively) and CKD (3.8%, 3.1% and 8.3%, respectively). The prevalences were significantly higher in the 'less than once a day' group than in the 'after every meal' group for DM (OR=2.03; 95% CI 1.29 to 3.21) and DL (OR=1.50; 95% CI 1.06 to 2.14), but not for HT, HUA and CKD.
conclusionsEven taking into account lifestyle habits, a lower frequency of toothbrushing was associated with high prevalences of DM and DL. Toothbrushing practices may be beneficial for oral health improvement and also for prevention of certain systemic diseases.
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