ArticleClinical journal of the American Society of Nephrology : CJASN2016
Annual Incidence of Nephrolithiasis among Children and Adults in South Carolina from 1997 to 2012.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 4 of them syntheses that pooled it.
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Who cites it
115 citing papers in PubMed, 4 syntheses or guidelines pooled it, 256 citations in OpenAlex.
- Gender Differences in Kidney Stone Disease (KSD): Findings from a Systematic Review.Current urology reports · 2021Pooled it
- Pooled it
- Prevalence of microhematuria in renal colic and urolithiasis: a systematic review and meta-analysis.BMC urology · 2020Pooled it
- Percutaneous nephrolithotomy versus retrograde intrarenal surgery for pediatric patients with upper urinary stones: a systematic review and meta-analysis.Urolithiasis · 2019Pooled it
- Metabolic and genetic spectrum of pediatric nephrolithiasis: insights from high-prevalence desert belt in India.Urolithiasis · 2026Observational
- Which over-the-counter herbal supplements are searched online? A review of internet trends, interest, and lithogenic potential of herbal health ingredients.Nutrition and health · 2026Article
- Trends in Kidney Stone Prevalence Among United States Adults With Diabetes: A Cross-Sectional Study From the NHANES Database, 2007-2020.Journal of diabetes research · 2026Article
- Case series - Beyond the stones: Thulium fiber laser-induced renal damage in children with proximal ureteral narrowing.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026Article
- The atherogenic index of plasma increases the risk of incident kidney stones: a nested case-control study in Chinese adults.Renal failure · 2025Article
- Distal Ureteric Stone Presenting Solely As Testicular Pain: Diagnostic Lessons From a Primary-Care Setting.Cureus · 2025Article
- Ureteroscopy in pediatric urolithiasis: techniques, challenges, and outcomes.World journal of urology · 2025Review
- Outcomes of Tiopronin and D-Penicillamine Therapy in Pediatric Cystinuria: A Clinical Comparison of Two Cases.Reports (MDPI) · 2025Article
- Ureteroscopy vs Shockwave Lithotripsy to Remove Kidney Stones in Children and Adolescents: A Nonrandomized Clinical Trial.JAMA network open · 2025Observational
- High-risk factors for urinary calculus recurrence in Chinese preschool children: findings from a medium-term follow-up survey.Translational andrology and urology · 2025Article
- Percutaneous Nephrolithotomy vs Ureteroscopy for Kidney Stones in Children.JAMA network open · 2025Observational
- Questionable role of opioids for analgesia in renal colic and its urological interventions.BJUI compass · 2025Review
- Association of accelerated biological aging with kidney stone: Insights from the U.S. National health and nutrition examination survey.Preventive medicine reports · 2025Article
- Successful Laparoscopic Ureterolithotomy to Remove a Large Ureteral Stone in an Infant: A Case Report.Cureus · 2025Article
- InducingKidney international reports · 2025Article
- Global burden of pediatric urolithiasis: A trend and health inequalities analysis from 1990 to 2021.European journal of pediatrics · 2025Article
55 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectivesThe prevalence of nephrolithiasis in the United States has increased substantially, but recent changes in incidence with respect to age, sex, and race are not well characterized. This study examined temporal trends in the annual incidence and cumulative risk of nephrolithiasis among children and adults living in South Carolina over a 16-year period. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We performed a population-based, repeated cross-sectional study using the US Census and South Carolina Medical Encounter data, which capture all emergency department visits, surgeries, and admissions in the state. The annual incidence of nephrolithiasis in South Carolina from 1997 to 2012 was estimated, and linear mixed models were used to estimate incidence rate ratios for age, sex, and racial groups. The cumulative risk of nephrolithiasis during childhood and over the lifetime was estimated for males and females in 1997 and 2012.
resultsAmong an at-risk population of 4,625,364 people, 152,925 unique patients received emergency, inpatient, or surgical care for nephrolithiasis. Between 1997 and 2012, the mean annual incidence of nephrolithiasis increased 1% annually from 206 to 239 per 100,000 persons. Among age groups, the greatest increase was observed among 15-19 year olds, in whom incidence increased 26% per 5 years (incidence rate ratio, 1.26; 95% confidence interval, 1.22 to 1.29). Adjusting for age and race, incidence increased 15% per 5 years among females (incidence rate ratio, 1.15; 95% confidence interval, 1.14 to 1.16) but remained stable for males. The incidence among blacks increased 15% more per 5 years compared with whites (incidence rate ratio, 1.15; 95% confidence interval, 1.14 to 1.17). These changes in incidence resulted in doubling of the risk of nephrolithiasis during childhood and a 45% increase in the lifetime risk of nephrolithiasis for women over the study period.
conclusionsThe incidence of kidney stones has increased among young patients, particularly women, and blacks.
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