Evidence map›Paper›PMID 26769590›Full record

ArticleEnvironmental science and pollution research international2016

Widespread occurrence and seasonal variation of pharmaceuticals in surface waters and municipal wastewater treatment plants in central Finland.

Petra C Lindholm-Lehto, Heidi S J Ahkola, Juha S Knuutinen, Sirpa H Herve

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 99 citations in OpenAlex.

  1. Article
  2. Review
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  8. Article
  9. Fate of Emerging Contaminants in High-Rate Activated Sludge Systems.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. Spatial and temporal variations of antibiotics in a tidal river.Environmental monitoring and assessment · 2020
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Suitability of passive sampling for the monitoring of pharmaceuticals in Finnish surface waters.Environmental science and pollution research international · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Petra C Lindholm-LehtoDepartment of Chemistry, University of Jyväskylä, P.O. Box 35, FI-40014, Jyväskylä, Finland. petra.lindholm-lehto@jyu.fi.
Heidi S J AhkolaFinnish Environment Institute (SYKE), Laboratory Centre, Ecotoxicology and Risk Assessment, Survontie 9A, FI-40500, Jyväskylä, Finland.
Juha S KnuutinenDepartment of Chemistry, University of Jyväskylä, P.O. Box 35, FI-40014, Jyväskylä, Finland.
Sirpa H HerveFinnish Environment Institute (SYKE), Laboratory Centre, Ecotoxicology and Risk Assessment, Survontie 9A, FI-40500, Jyväskylä, Finland.
Finnish Environment Institute · FIUniversity of Jyväskylä · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of five selected pharmaceuticals, consisting of four anti-inflammatory drugs, diclofenac, ibuprofen, ketoprofen, naproxen, and an antiepileptic drug carbamazepine, was determined at four municipal wastewater treatment plants (WWTPs) and in the receiving waterway in central Finland. The samples were taken from influents and effluents of the WWTPs and from surface water of six locations along the water way, including northern Lake Päijänne. In addition, seasonal variation in the area was determined by comparing the concentrations in the winter and summer. The samples were analyzed by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) in the multiple reaction monitoring mode. The concentrations in the influents and effluents ranged from hundreds of nanogram per liter to microgram per liter while ranged from tens of nanogram per liter in northern parts of the waterway to hundreds of nanogram per liter in northern Lake Päijänne near the city area. In addition, the concentrations were higher in the winter compared to summer time in surface water due to decreased temperature and solar irradiation. On the other hand, higher concentrations of ibuprofen, ketoprofen, and naproxen were found in summer at the WWTPs, possibly due to seasonal variations in consumption. In conclusion, there are considerable amounts of pharmaceuticals not only in influents and effluents of the WWTPs but also in lake water along the waterway and in northern Lake Päijänne.

Indexed as

AnticonvulsantsAnti-Inflammatory AgentsEnvironmental MonitoringFinlandLakesPharmaceutical PreparationsSeasonsTandem Mass SpectrometryWastewaterWater Pollutants, ChemicalWater PurificationAnticonvulsantsAnti-Inflammatory AgentsPharmaceutical PreparationsWastewaterWater Pollutants, ChemicalAntiepileptic drugAnti-inflammatory drugInfluent and effluentLake waterMunicipal wastewater treatment plantPharmaceuticalsSeasonal variation

Identifiers

PMID26769590
OpenAlexW2235525799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.