Evidence map›Paper›PMID 26769305›Full record

ReviewTherapeutic delivery2016

Graphene-based platforms for cancer therapeutics.

Sunny C Patel, Stephen Lee, Gaurav Lalwani, Cassandra Suhrland, Sayan Mullick Chowdhury, Balaji Sitharaman

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Advances in constructing biocompatible nanocarriers.Drug delivery and translational research · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. A Comprehensive Review of Inorganic Sonosensitizers for Sonodynamic Therapy.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Graphene-Related Nanomaterials for Biomedical Applications.Nanomaterials (Basel, Switzerland) · 2023
    Review
  13. Article
  14. Review
  15. Iranian journal of basic medical sciences · 2022
    Article
  16. Review
  17. Review
  18. Topographical nanostructures for physical sterilization.Drug delivery and translational research · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sunny C PatelDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794-5281, USA.
Stephen LeeDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794-5281, USA.
Gaurav LalwaniDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794-5281, USA.
Cassandra SuhrlandDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794-5281, USA.
Sayan Mullick ChowdhuryDepartment of Radiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Balaji SitharamanDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794-5281, USA.

Funding

Nanotechnology-based Theranostic Technology for Bone Tissue EngineeringDP2OD007394 · OD · STATE UNIVERSITY NEW YORK STONY BROOK · PI SITHARAMAN, BALAJI · 2010 to 2010
$2.4M
Functional Fluid Flow Regulated Bone RegenerationR01AR061821 · NIAMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI QIN, YI-XIAN · 2012 to 2016
$1.7M
NIAMS NIH HHS AR61821NIAMS NIH HHS R01 AR061821NIH HHS 1DP2OD007394NIH HHS DP2 OD007394
6 · The paper itself

Abstract

Graphene is a multifunctional carbon nanomaterial and could be utilized to develop platform technologies for cancer therapies. Its surface can be covalently and noncovalently functionalized with anticancer drugs and functional groups that target cancer cells and tissue to improve treatment efficacies. Furthermore, its physicochemical properties can be harnessed to facilitate stimulus responsive therapeutics and drug delivery. This review article summarizes the recent literature specifically focused on development of graphene technologies to treat cancer. We will focus on advances at the interface of graphene based drug/gene delivery, photothermal/photodynamic therapy and combinations of these techniques. We also discuss the current understanding in cytocompatibility and biocompatibility issues related to graphene formulations and their implications pertinent to clinical cancer management.

Indexed as

AnimalsAntineoplastic AgentsCell SurvivalDrug CarriersGene Transfer TechniquesGraphiteHumansMicroRNAsNeoplasmsPhotochemotherapyPhotosensitizing AgentsAntineoplastic AgentsDrug CarriersGraphiteMicroRNAsPhotosensitizing Agentsbiocompatibilitydrug/gene loadinggraphenephotodynamic therapyphotothermal therapy

Identifiers

PMID26769305
PMCPMC4976992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.