Evidence map›Paper›PMID 26769012›Full record

ArticleThorax2016

Optimising treatment of CF pulmonary exacerbation: a tough nut to crack.

Sonya L Heltshe, Christopher H Goss

Registry-linked trialAbstract readEditorialComment
In one paragraph

Article in Thorax, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04016571 (Parameters to Assess Response to Intra-Venous Antibiotic Treatment for Pulmonary Exacerbations in Cystic Fibrosis), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04016571 completednot on this map

Parameters to Assess Response to Intra-Venous Antibiotic Treatment for Pulmonary Exacerbations in Cystic Fibrosis

TypeobservationalSponsorBelfast Health and Social Care TrustRan2016 to 2019Enrolled31ConditionsCystic Fibrosis
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Sonya L HeltsheDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA Cystic Fibrosis Foundation Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, Washington, USA.ORCID http://orcid.org/0000-0003-2696-2382
Christopher H GossDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Washington, USA Cystic Fibrosis Foundation Therapeutics Development Network Coordinating Center, Seattle Children's Research Institute, Seattle, Washington, USA Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington School of Medicine Seattle, Seattle, Washington, USA.

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
Proof of Principle Evaluation of IV Gallium Nitrate in Patients with CFUM1HL119073 · NHLBI · UNIVERSITY OF WASHINGTON · PI GOSS, CHRISTOPHER HOOPER, SINGH, PRADEEP K · 2013 to 2017
$4.8M
Early Intervention in Pulmonary Exacerbation in CFR01HL103965 · NHLBI · UNIVERSITY OF WASHINGTON · PI GOSS, CHRISTOPHER HOOPER, LECHTZIN, NOAH · 2010 to 2014
$3.8M
The relationship of fecal microbiomes and nutritional status in CFR01DK095869 · NIDDK · UNIVERSITY OF WASHINGTON · PI HOFFMAN, LUCAS R, MILLER, SAMUEL I · 2014 to 2018
$3.2M
Investigating treatment resistance mechanisms in chronic bacterial infectionsR01AI101307 · NIAID · UNIVERSITY OF WASHINGTON · PI BRUCE, JAMES EDWARD, MANOIL, COLIN · 2012 to 2016
$2.9M
Regulation of host inflammatory responses and outcome in melioidosis by TLR5R01HL113382 · NHLBI · UNIVERSITY OF WASHINGTON · PI WEST, TIMOTHY EOIN · 2012 to 2016
$2.6M
Phase 2 Study of Intravenous Gallium Nitrate in the Treatment of Cystic FibrosisR01FD003704 · FDA · UNIVERSITY OF WASHINGTON · PI GOSS, CHRISTOPHER HOOPER · 2009 to 2018
$2.0M
Baby Observational and Nutritional Study of Cystic FibrosisR01DK095738 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI BOROWITZ, DRUCY, RAMSEY, BONNIE W · 2012 to 2015
$1.6M
FDA HHS R01 FD003704FDA HHS R01FD003704NHLBI NIH HHS R01 HL103965NHLBI NIH HHS R01HL103965NHLBI NIH HHS R01 HL113382NHLBI NIH HHS R01HL113382NHLBI NIH HHS UM1 HL119073NHLBI NIH HHS U M1HL119073NIAID NIH HHS R01 AI101307NIAID NIH HHS R01AI101307NIDDK NIH HHS P30 DK089507NIDDK NIH HHS P30DK089507NIDDK NIH HHS R01 DK095738NIDDK NIH HHS R01DK095738NIDDK NIH HHS R01 DK095869NIDDK NIH HHS R01DK095869
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HospitalizationCystic FibrosisFemaleHumansMaleSaline Solution, HypertonicSaline Solution, HypertonicBronchiectasisCystic Fibrosis

Identifiers

PMID26769012
PMCPMC5476924

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.