ReviewCellular and molecular life sciences : CMLS2016
Taking a bite out of spinal cord injury: do dental stem cells have the teeth for it?
Review in Cellular and molecular life sciences : CMLS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Human dental pulp stem cells for spinal cord injury.Stem cell research & therapy · 2025Review
- The potential therapeutic roles of dental pulp stem cells in spinal cord injury.Frontiers in molecular biosciences · 2024Review
- Anti-inflammatory effect of dental pulp stem cells.Frontiers in immunology · 2023Review
- Tumor necrosis factor α, and agonist and antagonists of cannabinoid receptor type 1 and type 2 alter the immunophenotype of stem cells from human exfoliated deciduous teeth.Einstein (Sao Paulo, Brazil) · 2023Article
- The human dental apical papilla promotes spinal cord repair through a paracrine mechanism.Cellular and molecular life sciences : CMLS · 2022Article
- Advances and Perspectives in Dental Pulp Stem Cell Based Neuroregeneration Therapies.International journal of molecular sciences · 2021Review
- Cell-Based Transplantation versus Cell Homing Approaches for Pulp-Dentin Complex Regeneration.Stem cells international · 2021Review
- Neuro-regenerative potential of dental stem cells: a concise review.Cell and tissue research · 2020Review
- Thermosensitive bFGF-Modified Hydrogel with Dental Pulp Stem Cells on Neuroinflammation of Spinal Cord Injury.ACS omega · 2020Article
- Dental Stem Cell-Derived Secretome/Conditioned Medium: The Future for Regenerative Therapeutic Applications.Stem cells international · 2020Review
- Biological Behavioral Alterations of the Post-neural Differentiated Dental Pulp Stem Cells Through anFrontiers in cell and developmental biology · 2020Article
- Mesenchymal Stem Cell Therapy for Spinal Cord Contusion: A Comparative Study on Small and Large Animal Models.Biomolecules · 2019Article
- Cerebrospinal Fluid and Photobiomodulation Effects on Neural Gene Expression in Dental Pulp Stem Cells.Journal of lasers in medical sciences · 2019Article
- Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion.Cellular and molecular life sciences : CMLS · 2018Article
- Metformin Protects Against Spinal Cord Injury by Regulating Autophagy via the mTOR Signaling Pathway.Neurochemical research · 2018Article
- Potential Roles of Dental Pulp Stem Cells in Neural Regeneration and Repair.Stem cells international · 2018Review
- Priming with FGF2 stimulates human dental pulp cells to promote axonal regeneration and locomotor function recovery after spinal cord injury.Scientific reports · 2017Article
- CD146 Expression Influences Periapical Cyst Mesenchymal Stem Cell Properties.Stem cell reviews and reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dental stem cells are an emerging star on a stage that is already quite populated. Recently, there has been a lot of hype concerning these cells in dental therapies, especially in regenerative endodontics. It is fitting that most research is concentrated on dental regeneration, although other uses for these cells need to be explored in more detail. Being a true mesenchymal stem cell, their capacities could also prove beneficial in areas outside their natural environment. One such field is the central nervous system, and in particular, repairing the injured spinal cord. One of the most formidable challenges in regenerative medicine is to restore function to the injured spinal cord, and as yet, a cure for paralysis remains to be discovered. A variety of approaches have already been tested, with graft-based strategies utilising cells harbouring appropriate properties for neural regeneration showing encouraging results. Here we present a review focusing on properties of dental stem cells that endorse their use in regenerative medicine, with particular emphasis on repairing the damaged spinal cord.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.