Evidence map›Paper›PMID 26768111›Full record

ArticleDrug testing and analysis

Approaches by the US National Institutes of Health to support rigorous scientific research on dietary supplements and natural products.

A J Kuszak, D C Hopp, J S Williamson, J M Betz, B C Sorkin

Abstract read
In one paragraph

Article in Drug testing and analysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Advancing botanical safety: A strategy for selecting, sourcing, and characterizing botanicals for developing toxicological tools.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2024
    Article
  7. Article
  8. Working with the natural complexity: Selection and characterization of black cohosh root extract for use in toxicology testing.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. A strategy for test article selection and phytochemical characterization of Echinacea purpurea extract for safety testing.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2020
    Article
  14. Review
  15. Naturally complex: Perspectives and challenges associated with Botanical Dietary Supplement Safety assessment.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2018
    Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

A J KuszakOffice of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., Bethesda, MD, 20892-7517, USA.
D C HoppDivision of Extramural Research, National Center for Complementary and Integrative Health, National Institutes of Health, 6707 Democracy Blvd., Bethesda, MD, 20892, USA.
J S WilliamsonDivision of Extramural Research, National Center for Complementary and Integrative Health, National Institutes of Health, 6707 Democracy Blvd., Bethesda, MD, 20892, USA.
J M BetzOffice of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., Bethesda, MD, 20892-7517, USA.
B C SorkinOffice of Dietary Supplements, National Institutes of Health, 6100 Executive Blvd., Bethesda, MD, 20892-7517, USA.ORCID http://orcid.org/0000-0001-8198-6921

Funding

Intramural NIH HHS Z99 OD999999
6 · The paper itself

Abstract

Mechanistic, clinical, and epidemiological research relevant to dietary supplements (DS) is supported by the U.S. National Institutes of Health. The Office of Dietary Supplements and the National Center for Complementary and Integrative Health promote the development and appropriate use of rigorous and comprehensive DS analyses which are critical for research reproducibility, particularly when the investigational DS include chemically complex natural products with unclear mechanisms of action.

Indexed as

National Institutes of Health (U.S.)Biological ProductsDietary SupplementsHumansReproducibility of ResultsResearch DesignUnited StatesBiological Productsdietary supplementsNational Institutes of Healthnatural productsresearch

Identifiers

PMID26768111
PMCPMC6661901

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.