ArticleNeuropsychiatric disease and treatment2016
Use of antidepressants in the treatment of major depressive disorder in primary care during a period of economic crisis.
Article in Neuropsychiatric disease and treatment, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
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Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evaluation of the Biases in the Studies that Assess the Effects of the Great Recession on Health. A Systematic Review.International journal of environmental research and public health · 2019Pooled it
- Impact of economic crises on mental health care: a systematic review.Epidemiology and psychiatric sciences · 2018Pooled it
- How did the use of psychotropic drugs change during the Great Recession in Portugal? A follow-up to the National Mental Health Survey.BMC psychiatry · 2020Article
- Optimization of Antidepressant use with Pharmacogenetic Strategies.Current genomics · 2017Article
- Psychotropic Drug Consumption and Employment Status in Time of Economic Crisis (2007-2011).The Psychiatric quarterly · 2017Article
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Authors and funding
2 authors.
Funding
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Abstract
objectiveTo describe antidepressant (AD) use in the treatment of major depressive disorder during a period of economic crisis. PATIENTS AND
methodsThis was a retrospective, observational study using population-based databases. Two periods were considered: 1) 2008-2009, precrisis, and 2) 2012-2013, economic crisis. Certain inclusion/exclusion criteria were taken into account for the study (initiation of AD treatment). Patients were followed up for 12 months. The main measures were use (defined daily doses), epidemiologic measures, strategies used and treatment persistence, referrals, and use of resources. Statistical significance was set at P<0.05.
resultsIn the precrisis period, 3,662 patients were enrolled, and 5,722 were enrolled in the period of economic crisis. Average age was 58.8 years and 65.4% were women. Comparing the two periods, major depressive disorder prevalence was 5.4% vs 8.1%, P<0.001. During the period of economic crisis, AD use rose by 35.2% and drug expenditures decreased by 38.7%. Defined daily dose per patient per day was 10.0 mg vs 13.5 mg, respectively, P<0.001. At 12-month follow-up, the majority of patients (60.8%) discontinued the treatment or continued on the same medication as before, and in 23.3% a change of AD was made.
conclusionPrimary health care professionals are highly involved in the management of the illness; in addition, during the period of economic crisis, patients with major depressive disorder showed higher rates of prevalence of the illness, with increased use of AD drugs.
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