ArticleIntelligence
Intelligence in youth and health at age 50.
Article in Intelligence. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
60 citing papers in PubMed, 3 syntheses or guidelines pooled it, 136 citations in OpenAlex.
- Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.Nature genetics · 2018Pooled it
- Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.Nature communications · 2018Pooled it
- Impact of meningitis on intelligence and development: A systematic review and meta-analysis.PloS one · 2017Pooled it
- The relationship between chronotype and intelligence: the importance of work timing.Scientific reports · 2020Trial
- Article
- Shared genetic architecture between the topology of brain white matter structural connectome and fluid intelligence.Communications biology · 2026Article
- Sleepiness but neither fluid nor crystallized intelligence can be predicted from resting-state electroencephalography - Evidence from the large scale CoScience EEG-Personality Project.Cognitive, affective & behavioral neuroscience · 2025Article
- Adolescent IQ and performance-based measures of physical function in old age: a 54-year longitudinal study.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025Article
- Adverse Childhood Experiences, Neurocognitive Functions, and Long-Term Mortality Risk.JAMA network open · 2025Article
- Stability of general cognitive ability from infancy to adulthood: A combined twin and genomic investigation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Multilevel multiverse meta-analysis indicates lower IQ as a risk factor for physical and mental illness.Communications psychology · 2025Article
- Mendelian Randomization Estimates the Effects of Plasma and Cerebrospinal Fluid Proteins on Intelligence, Fluid Intelligence Score, and Cognitive Performance.Molecular neurobiology · 2025Article
- Mental health of intellectually gifted individuals: investigating the nonlinearity of the relationship between intelligence and general mental health.Health psychology report · 2025Article
- Bidirectional Associations of Depressive Symptoms and Cognitive Function Over Time.JAMA network open · 2024Article
- General and specific patterns of cortical gene expression as spatial correlates of complex cognitive functioning.Human brain mapping · 2024Article
- Exploring the influences of education, intelligence and income on mental disorders.General psychiatry · 2024Article
- Personalized functional brain network topography is associated with individual differences in youth cognition.Nature communications · 2023Article
- Multivariate prediction of cognitive performance from the sleep electroencephalogram.NeuroImage · 2023Article
- General and specific patterns of cortical gene expression as spatial correlates of complex cognitive functioning.bioRxiv : the preprint server for biology · 2023Article
- Cardiff Online Cognitive Assessment in a National Sample: Cross-Sectional Web-Based Study.Journal of medical Internet research · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe link between intelligence in youth and all-cause mortality in later-life is well established. To better understand this relationship, the current study examines the links between pre-morbid intelligence and a number of specific health outcomes at age 50 using the NLSY-1979 cohort.
methodsParticipants were the 5793 participants in the NLSY-79 who responded to questions about health outcomes at age 50. Sixteen health outcomes were examined: two were summary measures (physical health and functional limitation), 9 were diagnosed illness conditions, 4 were self-reported conditions, and one was a measure of general health status. Linear and logistic regressions were used, as appropriate, to examine the relationship between intelligence in youth and the health outcomes. Age, sex and both childhood and adult SES, and its sub-components - income, education, & occupational prestige - are all adjusted for separately. RESULTS &
conclusionHigher pre-morbid intelligence is linked with better physical health at age 50, and a lower risk for a number of chronic health conditions. For example, a 1 SD higher score in IQ was significantly associated with increased odds of having good, very good, or excellent health, with an odds ratio of 1.70 (C.I. 1.55-1.86). Thirteen of the illness outcomes were significantly and negatively associated with IQ in youth; the odds ratios ranged from 0.85 for diabetes/high blood sugar to 0.65 for stroke, per one standard deviation higher score in IQ. Adjustment for childhood SES led to little attenuation but adult SES partially mediated the relationship for a number of conditions. Mediation by adult SES was not consistently explained by any one of its components-income, education, and occupation status. The current findings contribute to our understanding of lower intelligence as a risk factor for poor health and how this may contribute to health inequalities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.