Evidence map›Paper›PMID 26766231›Full record

ArticleCurrent biology : CB2016

Neuroscience: A Distributed Neural Network Controls REM Sleep.

John Peever, Patrick M Fuller

Abstract readComment
In one paragraph

Article in Current biology : CB, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Nightmares or a crippling reality? A review on sleep paralysis.Journal of family medicine and primary care · 2025
    Review
  5. Dreams interrupted: characteristics of REM sleep-associated seizures and status epilepticus.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  6. Interactions between Arousal State and COThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  7. Article
  8. Review
  9. Sleep during and following critical illness: A narrative review.World journal of critical care medicine · 2023
    Review
  10. Article
  11. NMDA Receptors in the Lateral Preoptic Hypothalamus Are Essential for Sustaining NREM and REM Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Brain Clocks, Sleep, and Mood.Advances in experimental medicine and biology · 2021
    Review
  17. Lewy Body Degenerations as Neuropsychiatric Disorders.The Psychiatric clinics of North America · 2020
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

John PeeverDepartments of Cell and Systems Biology and Physiology, University of Toronto, Toronto, ON, M5S 3G5, Canada. Electronic address: john.peever@utoronto.ca.
Patrick M FullerDepartment of Neurology, Beth Israel Deaconess Medical Center and Division of Sleep Medicine, Harvard Medical School, Boston, MA 02215, USA. Electronic address: pfuller@bidmc.harvard.edu.

Funding

Molecular-Genetic Dissection of Subcortical Circuitry Regulating ArousalR01NS073613 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Patrick M Fuller · 2011 to 2026
$5.5M
Brainstem regulation of sleepR01NS092652 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI FULLER, PATRICK M · 2015 to 2019
$2.2M
NINDS NIH HHS R01 NS073613NINDS NIH HHS R01 NS092652
6 · The paper itself

Abstract

How does the brain control dreams? New science shows that a small node of cells in the medulla - the most primitive part of the brain - may function to control REM sleep, the brain state that underlies dreaming.

Indexed as

AnimalsFemaleGABAergic NeuronsMaleMedulla OblongataSleep, REM

Identifiers

PMID26766231
PMCPMC5846126

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.