ArticleMedical image analysis2016
Shape analysis of hypertrophic and hypertensive heart disease using MRI-based 3D surface models of left ventricular geometry.
Article in Medical image analysis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Effects of vessel morphology on aortic hemodynamics: a statistical shape and CFD investigation.Medical & biological engineering & computing · 2026Article
- 3D cardiac shape analysis with variational point cloud autoencoders for myocardial infarction prediction and virtual heart synthesis.Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society · 2025Article
- Left ventricular anatomy in obstructive hypertrophic cardiomyopathy: beyond basal septal hypertrophy.European heart journal. Cardiovascular Imaging · 2023Article
- Toward ECG-based analysis of hypertrophic cardiomyopathy: a novel ECG segmentation method for handling abnormalities.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- On the Left Ventricular Remodeling of Patients with Stenotic Aortic Valve: A Statistical Shape Analysis.Bioengineering (Basel, Switzerland) · 2021Article
- Diffeomorphic Upsampling of Serially Acquired Sparse 2D Cross-Sections in Cardiac MRI.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019Article
- Mapping morphological shape as a high-dimensional functional curve.Briefings in bioinformatics · 2018Article
- Statistical shape modeling of the left ventricle: myocardial infarct classification challenge.IEEE journal of biomedical and health informatics · 2018Article
- Investigating Cardiac Motion Patterns Using Synthetic High-Resolution 3D Cardiovascular Magnetic Resonance Images and Statistical Shape Analysis.Frontiers in pediatrics · 2017Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
Abstract
The focus of this study was to develop advanced mathematical tools to construct high-resolution 3D models of left-ventricular (LV) geometry to evaluate focal geometric differences between patients with hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD) using cardiac magnetic resonance (MR) cross-sectional images. A limiting factor in 3D analysis of cardiac MR cross-sections is the low out-of-plane resolution of the acquired images. To overcome this problem, we have developed a mathematical framework to construct a population-based high-resolution 3D LV triangulated surface (template) in which an iterative matching algorithm maps a surface mesh of a normal heart to a set of cross-sectional contours that were extracted from short-axis cine cardiac MR images of patients who were diagnosed with either HCM or HHD. A statistical analysis was conducted on deformations that were estimated at each surface node to identify shape differences at end-diastole (ED), end-systole (ES), and motion-related shape variation from ED to ES. Some significant shape difference in radial thickness was detected at ES. Differences of LV 3D surface geometry were identified focally on the basal anterior septum wall. Further research is needed to relate these findings to the HCM morphological substrate and to design a classifier to discriminate among different etiologies of LV hypertrophy.
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