ArticleBiosensors & bioelectronics2016
Ultrasensitive detection of influenza viruses with a glycan-based impedimetric biosensor.
Article in Biosensors & bioelectronics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 83 citations in OpenAlex.
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- Aptamer-Based Approaches for Influenza Virus Detection: A Systematic Review.Health science reports · 2026Review
- Aptamer-Based Biosensors for Rapid Detection and Early Warning of Food Contaminants: From Selection to Field Applications.Molecules (Basel, Switzerland) · 2025Review
- Electrochemical biosensors based on the 3D immobilization of capture probes for influenza virus detection.RSC advances · 2025Review
- Metal-Mediated Il-8 Binding to Heparan Sulfate Evaluated by Electrochemical Impedance Spectroscopy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Impedimetric Characterization of NanA Structural Domains Activity on Sialoside-Containing Interfaces.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- Surface-Controlled Sialoside-Based Biosensing of Viral and Bacterial Neuraminidases.Langmuir : the ACS journal of surfaces and colloids · 2024Article
- Recent Developments in Electrochemical-Impedimetric Biosensors for Virus Detection.International journal of molecular sciences · 2022Review
- Glycan-Based Electrochemical Biosensors: Promising Tools for the Detection of Infectious Diseases and Cancer Biomarkers.Molecules (Basel, Switzerland) · 2022Review
- Genosensors as an alternative diagnostic sensing approaches for specific detection of virus species: A review of common techniques and outcomes.Trends in analytical chemistry : TRAC · 2022Review
- Hybrid Nanobioengineered Nanomaterial-Based Electrochemical Biosensors.Molecules (Basel, Switzerland) · 2022Review
- Aptamers in Virology-A Consolidated Review of the Most Recent Advancements in Diagnosis and Therapy.Pharmaceutics · 2021Review
- Electrochemical investigations for COVID-19 detection-A comparison with other viral detection methods.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2021Article
- Advancements in electrochemical biosensing for respiratory virus detection: A review.Trends in analytical chemistry : TRAC · 2021Review
- A changing trend in diagnostic methods of Influenza A (H3N2) virus in human: a review.3 Biotech · 2021Review
- Avidin-biotin complex-based capture coating platform for universal Influenza virus immobilization and characterization.PloS one · 2021Article
- The research of aptamer biosensor technologies for detection of microorganism.Applied microbiology and biotechnology · 2020Review
- Biosensors for the detection of respiratory viruses: A review.Talanta open · 2020Review
- Nanobiosensors for the Detection of Novel Coronavirus 2019-nCoV and Other Pandemic/Epidemic Respiratory Viruses: A Review.Sensors (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
An ultrasensitive impedimetric glycan-based biosensor for reliable and selective detection of inactivated, but intact influenza viruses H3N2 was developed. Such glycan-based approach has a distinct advantage over antibody-based detection of influenza viruses since glycans are natural viral receptors with a possibility to selectively distinguish between potentially pathogenic influenza subtypes by the glycan-based biosensors. Build-up of the biosensor was carefully optimized with atomic force microscopy applied for visualization of the biosensor surface after binding of viruses with the topology of an individual viral particle H3N2 analyzed. The glycan biosensor could detect a glycan binding lectin with a limit of detection (LOD) of 5 aM. The biosensor was finally applied for analysis of influenza viruses H3N2 with LOD of 13 viral particles in 1 μl, what is the lowest LOD for analysis of influenza viral particles by the glycan-based device achieved so far. The biosensor could detect H3N2 viruses selectively with a sensitivity ratio of 30 over influenza viruses H7N7. The impedimetric biosensor presented here is the most sensitive glycan-based device for detection of influenza viruses and among the most sensitive antibody or aptamer based biosensor devices.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.