ArticleMedicine2016
Clinicopathologic Features and Clinical Outcomes of Esophageal Gastrointestinal Stromal Tumor: Evaluation of a Pooled Case Series.
Article in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Meta-analysis comparing laparoscopic versus open resection for gastric gastrointestinal stromal tumors larger than 5 cm.BMC cancer · 2017Pooled it
- Clinicopathological feature and prognosis of primary hepatic gastrointestinal stromal tumor.Cancer medicine · 2016Pooled it
- The Rare Upper Thoracic and Cervical Esophageal GIST Resected Through Thoracoscopic Esophageal Mobilization and a Cervical Approach: A Case Report.Cancer reports (Hoboken, N.J.) · 2025Review
- Expanding the role of endoscopic resection in esophageal gastrointestinal stromal tumors: Insights and challenges.World journal of gastroenterology · 2025Article
- Characterization of subepithelial tumors of upper gastrointestinal tract by endoscopic ultrasound.World journal of gastroenterology · 2025Article
- Endoscopic treatment outcome of oesophageal gastrointestinal stromal tumours.World journal of gastroenterology · 2025Article
- Successfully treated esophageal gastrointestinal stromal tumor by minimally invasive esophagectomy followed by imatinib therapy: a case report.Annals of medicine and surgery (2012) · 2025Article
- Rare malignant neoplasm of the esophagus: current status and future perspectives.Japanese journal of clinical oncology · 2024Review
- Identification of a novelFrontiers in oncology · 2022Article
- A nationwide survey on esophageal gastrointestinal stromal tumors at accredited institutions by the Japan Esophageal Society.Esophagus : official journal of the Japan Esophageal Society · 2021Article
- Giant hepatic extra-gastrointestinal stromal tumor treated with cytoreductive surgery and adjuvant systemic therapy: A case report and review of literature.World journal of gastrointestinal surgery · 2021Article
- Clinicopathologic features and outcomes of gastrointestinal stromal tumors arising from the esophagus and gastroesophageal junction.Journal of gastrointestinal oncology · 2018Article
- Strategy for esophageal non-epithelial tumors based on a retrospective analysis of a single facility.Esophagus : official journal of the Japan Esophageal Society · 2018Article
- Gastrointestinal stromal tumor of the esophagus: current issues of diagnosis, surgery and drug therapy.Translational gastroenterology and hepatology · 2018Review
- Clinicopathological features and prognosis of mesenteric gastrointestinal stromal tumor: evaluation of a pooled case series.Oncotarget · 2017Article
- Clinicopathological features and prognosis of omental gastrointestinal stromal tumor: evaluation of a pooled case series.Scientific reports · 2016Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinicopathologic features and clinical outcomes of gastrointestinal stromal tumors (GISTs) in esophagus are limited, because of the relatively rare incidence of esophageal GISTs. Therefore, the aim of the current study was to investigate the clinicopathologic features and clinical outcomes of esophageal GISTs, and to investigate the potential factors that may predict prognosis.Esophageal GIST cases were obtained from our center and from case reports and clinical studies extracted from MEDLINE. Clinicopathologic features and survivals were analyzed and compared with gastric GISTs from our center.The most common location was lower esophagus (86.84%), followed by middle and upper esophagus (11.40% and 1.76%). The majority of esophageal GISTs were classified as high-risk category (70.83%). Mitotic index was correlated with histologic type, mutational status, and tumor size. The 5-year disease-free survival and disease-specific survival were 65.1% and 65.9%, respectively. Tumor size, mitotic index, and National Institutes of Health risk classification were associated with prognosis of esophageal GISTs. Only tumor size, however, was the independent risk factor for the prognosis of esophageal GISTs. In comparison to gastric GISTs, the distribution of tumor size, histologic type, and National Institutes of Health risk classification were significantly different between esophageal GISTs and gastric GISTs. The disease-free survival and disease-specific survival of esophageal GISTs were significantly lower than that of gastric GISTs.The most common location for esophageal GISTs was lower esophagus, and most of the esophageal GISTs are high-risk category. Tumor size was the independent risk factor for the prognosis of esophageal GISTs. Esophageal GISTs differ significantly from gastric GISTs in respect to clinicopathologic features. The prognosis of esophageal GISTs was worse than that of gastric GISTs.
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