Evidence map›Paper›PMID 26765328›Full record

ArticlePloS one2016

Acquired and Transmitted Multidrug Resistant Tuberculosis: The Role of Social Determinants.

Anna Odone, Roger Calderon, Mercedes C Becerra, Zibiao Zhang, Carmen C Contreras, Rosa Yataco, Jerome Galea, Leonid Lecca, Matthew H Bonds, Carole D Mitnick and 1 more

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Impact of Diabetes Mellitus in Tuberculosis (TB) Patients on TB Transmission.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  6. The Role of Youths in Within-Household Tuberculosis Transmission: A Household Contact Cohort Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  7. Review
  8. Who Transmits Tuberculosis to Whom: A Cross-Sectional Analysis of a Cohort Study in Lima, Peru.American journal of respiratory and critical care medicine · 2024
    Article
  9. Latent TB and depressive symptoms in household contacts of persons with active TB.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  10. Culture-negative TB: clinical characteristics, risk factors and treatment outcomes.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Rifampicin-ResistantInfection and drug resistance · 2020
    Article
  18. International collaboration among medical societies is an effective way to boost Latin American production of articles on tuberculosis.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019
    Article
  19. Primary bacillary resistance in multidrug-resistant tuberculosis and predictive factors associated with cure at a referral center in São Paulo, Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anna OdoneUnit of Public Health, Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, Parma, Italy.
Roger CalderonPartners In Health / Socios En Salud, Boston, Massachusetts, United States of America and Lima, Peru.
Mercedes C BecerraPartners In Health / Socios En Salud, Boston, Massachusetts, United States of America and Lima, Peru.
Zibiao ZhangDivision of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, United States of America.
Carmen C ContrerasPartners In Health / Socios En Salud, Boston, Massachusetts, United States of America and Lima, Peru.
Rosa YatacoPartners In Health / Socios En Salud, Boston, Massachusetts, United States of America and Lima, Peru.
Jerome GaleaPartners In Health / Socios En Salud, Boston, Massachusetts, United States of America and Lima, Peru.
Leonid LeccaPartners In Health / Socios En Salud, Boston, Massachusetts, United States of America and Lima, Peru.
Matthew H BondsDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, United States of America.
Carole D MitnickPartners In Health / Socios En Salud, Boston, Massachusetts, United States of America and Lima, Peru.
Megan B MurrayPartners In Health / Socios En Salud, Boston, Massachusetts, United States of America and Lima, Peru.

Funding

Epidemiology of multidrug-resistant tuberculosis in PeruU01AI057786 · NIAID · HARVARD MEDICAL SCHOOL · PI BECERRA, MERCEDES C · 2009 to 2010
$1.2M
NIAID NIH HHS U01 AI057786PHS HHS U19 A1076217
6 · The paper itself

Abstract

Although risk factors for multi-drug resistant tuberculosis are known, few studies have differentiated between acquired and transmitted resistance. It is important to identify factors associated with these different mechanisms to optimize control measures. We conducted a prospective cohort study of index TB patients and their household contacts in Lima, Peru to identify risk factors associated with acquired and transmitted resistance, respectively. Patients with higher socioeconomic status (SES) had a 3-fold increased risk of transmitted resistance compared to those with lower SES when acquired resistance served as the baseline. Quality of housing mediated most of the impact of SES.

Indexed as

AdolescentAdultAgedFemaleHumansMaleMiddle AgedPeruSocioeconomic FactorsTuberculosis, Multidrug-ResistantTuberculosis, Pulmonary

Identifiers

PMID26765328
PMCPMC4713093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.