ReviewBlood purification2016
Intradialytic Hypoxemia in Chronic Hemodialysis Patients.
Review in Blood purification, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 61 citations in OpenAlex.
- Changes in Central Venous Oxygen Saturation during Inpatient Hemodialysis.Blood purification · 2026Article
- Short-Term Effects of Intradialytic Hypoxemia on Plasma Markers of Hypoxia.International journal of molecular sciences · 2026Article
- Frequency-domain broadband near-infrared spectroscopy for noninvasive monitoring of fluid volume status during hemodialysis.Biophotonics discovery · 2026Article
- Predictive performance of central venous oxygen saturation, lactate, base excess, and alactic base excess for intradialytic hypotension.BMC nephrology · 2025Observational
- Evaluation of intradialytic hypoxemia development in intensive care patients.BMC nephrology · 2025Observational
- Intermittent hypoxemia during hemodialysis: AI-based identification of arterial oxygen saturation saw-tooth pattern.BMC nephrology · 2025Article
- Utility of Central Venous Oxygen Saturation Gradient in Predicting Mortality in Dialysis with Catheter Access.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Assessment and management of emergencies during haemodialysis.Journal of nephrology · 2025Review
- Multiple automated machine-learning prediction models for postoperative reintubation in patients with acute aortic dissection: a multicenter cohort study.Frontiers in medicine · 2025Article
- Article
- Hemoincompatibility in Hemodialysis-Related Therapies and Their Health Economic Perspectives.Journal of clinical medicine · 2024Article
- Respiratory sarcopenia screening in dialysis patients: cross-sectional and multicentre study protocol.BMC nephrology · 2024Article
- Digital health technology to support care and improve outcomes of chronic kidney disease patients: as a case illustration, the Withings toolkit health sensing tools.Frontiers in nephrology · 2023Review
- Identification of arterial oxygen intermittency in oximetry data.Scientific reports · 2022Article
- Hidden risks associated with conventional short intermittent hemodialysis: A call for action to mitigate cardiovascular risk and morbidity.World journal of nephrology · 2022Review
- Patients with hemodialysis-induced hypoxemia had a poor prognosis of COVID-19.Renal replacement therapy · 2022Article
- A porcine model of hemodialyzer reactions: roles of complement activation and rinsing back of extracorporeal blood.Renal failure · 2021Article
- Multitargeted interventions to reduce dialysis-induced systemic stress.Clinical kidney journal · 2021Review
- Prolonged Intradialytic Hypoxemia Is Associated With Functional Disturbances in Erythrocytes.Kidney international reports · 2021Article
- Comparative analysis of therapeutic effects between medium cut-off and high flux dialyzers using metabolomics and proteomics: exploratory, prospective study in hemodialysis.Scientific reports · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
When kidney failure occurs, patients are at risk for fluid overload states, which can cause pulmonary edema, pleural effusions, and upper airway obstruction. Kidney disease is also associated with impaired respiratory function, as in central sleep apnea or chronic obstructive pulmonary disease. Hence, respiratory and renal diseases are frequently coexisting. Hypoxemia is the terminal pathway of a multitude of respiratory pathologies. The measurement of oxygen saturation (SO2) is a basic and commonly used tool in clinical practice. Both arterial oxygen saturation (SaO2) and central venous oxygen saturation (ScvO2) can be easily obtained in hemodialysis (HD) patients, SaO2 from an arteriovenous access and ScvO2 from a central catheter. Here, we give a brief overview of the anatomy and physiology of the respiratory system, and the different technologies that are currently available to measure oxygen status in dialysis patients. We then focus on literature regarding intradialytic SaO2 and ScvO2. Lastly, we present clinical vignettes of intradialytic drops in SaO2 and ScvO2 in association with different symptoms and clinical scenarios with an emphasis on the pathophysiology of these cases. Given the fact that in the general population hypoxemia is associated with adverse outcomes, including increased mortality, cardiac arrhythmias and cardiovascular events, we posit that intradialytic SO2 may serve as a potential marker to identify HD patients at increased risk for morbidity and mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.