Evidence map›Paper›PMID 26764485›Full record

ArticlePloS one2016

Decompressive Hemicraniectomy in a South American Population--Morbidity and Outcomes Analysis.

Roberto Bezerra Vital, Pedro Tadao Hamamoto Filho, Gustavo Jose Luvizutto, Luis Gustavo Ducati, Gabriel Pereira Braga, Helio Rubens de Carvalho Nunes, Flavio Ramalho Romero, Eliana Marisa Ganem, Marco Antonio Zanini, Rodrigo Bazan

Abstract readEvaluation Study
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Roberto Bezerra VitalDepartment of Neurology, Psychology and Psychiatry at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Pedro Tadao Hamamoto FilhoDepartment of Neurology, Psychology and Psychiatry at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Gustavo Jose LuvizuttoDepartment of Neurology, Psychology and Psychiatry at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Luis Gustavo DucatiDepartment of Neurology, Psychology and Psychiatry at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Gabriel Pereira BragaDepartment of Neurology, Psychology and Psychiatry at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Helio Rubens de Carvalho NunesDepartment of Public Health Medicine at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Flavio Ramalho RomeroDepartment of Neurology, Psychology and Psychiatry at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Eliana Marisa GanemDepartment of Anesthesiology at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Marco Antonio ZaniniDepartment of Neurology, Psychology and Psychiatry at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.
Rodrigo BazanDepartment of Neurology, Psychology and Psychiatry at Botucatu Medical School, Univ Estadual Paulista, Botucatu, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalignant cerebral artery strokes have a poor prognosis, with nearly 80% of mortality in some series despite intensive care. After a large randomized trial, decompressive hemicraniectomy has been performed more often in stroke patients. Here, we describe patients in a tertiary teaching hospital in Brazil, emphasizing the impact of age on outcomes.

methodsA retrospective cohort of patients, with malignant strokes which received a decompressive hemicraniectomy, from paper and electronic medical records, from January 2010 to December 2013 was divided into two groups according to age.

resultsThe final analysis included 60 patients. The overall mortality was higher among patients older than 60 yrs (67% vs. 41%; p = 0.039), whose group also had a worse outcome (76% with mRS 5 or 6) at 90 days (OR 3.91 CI95% 1.30-11.74), whereas only 24% had mRS of 0-4 (p = 0.015). All patients who presented with sepsis died (p = 0.003). The incidence of pulmonary infection was very high in the elderly group (76%) with significant intergroup differences (p = 0.027, OR 8.32 CI95% 0.70-98.48).

conclusionsOlder patients present more commonly with infections, more disabilities and a higher mortality, highlighting very poor results in elderly population. These results should be proved with a South American trial, and if confirmed, it can impact on future decisions regarding decompressive craniectomy for acute ischemic stroke in our region.

Indexed as

AdultAgedAged, 80 and overBrain IschemiaDecompressive CraniectomyFemaleHumansMaleMiddle AgedSouth AmericaStroke

Identifiers

PMID26764485
PMCPMC4713228

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.