ArticlePlant physiology2016
H3K36ac Is an Evolutionary Conserved Plant Histone Modification That Marks Active Genes.
Article in Plant physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Positional grammar of transcription factor binding partitions developmental and stress-response regulation in plants.Nature communications · 2026Article
- Enhanced plant bottom-up histone proteomics.Journal of experimental botany · 2026Article
- SIRT7 links H3K36ac epigenetic regulation with genome maintenance in the mouse testis.Nature communications · 2026Article
- Histone H3 mutations and their impact on genome stability maintenance.Biochemical Society transactions · 2024Review
- Symphonies of Growth: Unveiling the Impact of Sound Waves on Plant Physiology and Productivity.Biology · 2024Review
- Regulation of Disease-Resistance Genes against CWMV Infection by NbHAG1-Mediated H3K36ac.International journal of molecular sciences · 2024Article
- Review
- Endosperm and Maternal-specific expression of EIN2 in the endosperm affects endosperm cellularization and seed size in Arabidopsis.Genetics · 2023Article
- CaSWC4 regulates the immunity-thermotolerance tradeoff by recruiting CabZIP63/CaWRKY40 to target genes and activating chromatin in pepper.PLoS genetics · 2022Article
- Acetylproteomics analyses reveal critical features of lysine-ε-acetylation in Arabidopsis and a role of 14-3-3 protein acetylation in alkaline response.Stress biology · 2022Article
- Histone variants and modifications during abiotic stress response.Frontiers in plant science · 2022Review
- Histone methyltransferases SDG33 and SDG34 regulate organ-specific nitrogen responses in tomato.Frontiers in plant science · 2022Article
- Mysteries of gene regulation: Promoters are not the sole triggers of gene expression.Computational and structural biotechnology journal · 2022Article
- Regulation of RNA polymerase II activity is essential for terminal erythroid maturation.Blood · 2021Article
- Leveraging histone modifications to improve genome annotations.G3 (Bethesda, Md.) · 2021Article
- HAG1 and SWI3A/B control of male germ line development in P. patens suggests conservation of epigenetic reproductive control across land plants.Plant reproduction · 2021Article
- H3.1K27me1 maintains transcriptional silencing and genome stability by preventing GCN5-mediated histone acetylation.The Plant cell · 2021Article
- Histone acetylation dynamics regulating plant development and stress responses.Cellular and molecular life sciences : CMLS · 2021Review
- Cataloging Posttranslational Modifications in Plant Histones.Advances in experimental medicine and biology · 2021Article
- An optimised chromatin immunoprecipitation (ChIP) method for starchy leaves of Nicotiana benthamiana to study histone modifications of an allotetraploid plant.Molecular biology reports · 2020Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
In eukaryotic cells, histones are subject to a large number of posttranslational modifications whose sequential or combinatorial action affects chromatin structure and genome function. We identified acetylation at Lys-36 in histone H3 (H3K36ac) as a new chromatin modification in plants. The H3K36ac modification is evolutionary conserved in seed plants, including the gymnosperm Norway spruce (Picea abies) and the angiosperms rice (Oryza sativa), tobacco (Nicotiana tabacum), and Arabidopsis (Arabidopsis thaliana). In Arabidopsis, H3K36ac is highly enriched in euchromatin but not in heterochromatin. Genome-wide chromatin immunoprecipitation sequencing experiments revealed that H3K36ac peaks at the 5' end of genes, mainly on the two nucleosomes immediately distal to the transcription start site, independently of gene length. H3K36ac overlaps with H3K4me3 and the H2A.Z histone variant. The histone acetyl transferase GCN5 and the histone deacetylase HDA19 are required for H3K36ac homeostasis. H3K36ac and H3K36me3 show negative crosstalk, which is mediated by GCN5 and the histone methyl transferase SDG8. Although H3K36ac is associated with gene activity, we did not find a linear relationship between H3K36ac and transcript levels, suggesting that H3K36ac is a binary indicator of transcription.
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