Evidence map›Paper›PMID 26764206›Full record

ArticleAmerican journal of physiology. Renal physiology2016

Novel application of complementary imaging techniques to examine in vivo glucose metabolism in the kidney.

Takashi Hato, Allon N Friedman, Henry Mang, Zoya Plotkin, Shataakshi Dube, Gary D Hutchins, Paul R Territo, Brian P McCarthy, Amanda A Riley, Kumar Pichumani and 4 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 26 citations in OpenAlex.

  1. Organ-Specific Perfusion Response to Adenosine as Measured Using Total-Body PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. The Indiana O'Brien Center for Advanced Renal Microscopic Analysis.American journal of physiology. Renal physiology · 2021
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. HyperpolarisedMagma (New York, N.Y.) · 2020
    Review
  11. Review
  12. Article
  13. Article
  14. Kidney Imaging: Intravital Microscopy.Methods in molecular biology (Clifton, N.J.) · 2018
    Article
  15. Advances in Renal Cell Imaging.Seminars in nephrology · 2018
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Takashi HatoDivision of Nephrology, Department of Medicine, Indiana University, Indianapolis, Indiana.
Allon N FriedmanDivision of Nephrology, Department of Medicine, Indiana University, Indianapolis, Indiana.
Henry MangDivision of Nephrology, Department of Medicine, Indiana University, Indianapolis, Indiana.
Zoya PlotkinDivision of Nephrology, Department of Medicine, Indiana University, Indianapolis, Indiana.
Shataakshi DubeDivision of Nephrology, Department of Medicine, Indiana University, Indianapolis, Indiana.
Gary D HutchinsDepartment of Radiology and Imaging Sciences and the Indiana Institute for Biomedical Imaging Sciences, Indiana University, Indianapolis, Indiana.
Paul R TerritoDepartment of Radiology and Imaging Sciences and the Indiana Institute for Biomedical Imaging Sciences, Indiana University, Indianapolis, Indiana.
Brian P McCarthyDepartment of Radiology and Imaging Sciences and the Indiana Institute for Biomedical Imaging Sciences, Indiana University, Indianapolis, Indiana.
Amanda A RileyDepartment of Radiology and Imaging Sciences and the Indiana Institute for Biomedical Imaging Sciences, Indiana University, Indianapolis, Indiana.
Kumar PichumaniAdvanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Craig R MalloyAdvanced Imaging Research Center, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
Robert A HarrisDepartment of Biochemistry and Molecular Biology, Indiana University, Indianapolis, Indiana.
Pierre C DagherDivision of Nephrology, Department of Medicine, Indiana University, Indianapolis, Indiana.
Timothy A SuttonDivision of Nephrology, Department of Medicine, Indiana University, Indianapolis, Indiana; tsutton2@iu.edu.
Indiana University – Purdue University Indianapolis · USSouthwestern Medical Center · USThe University of Texas Southwestern Medical Center · US

Funding

PROBE DELIVERY COREP30DK079312 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MOLITORIS, BRUCE A · 2007 to 2021
$17.1M
Modifying kidney injury through p53 signaling.R01DK099345 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI DAGHER, PIERRE C, SUTTON, TIMOTHY ALAN · 2014 to 2017
$1.4M
NIDDK NIH HHS P30 DK079312NIDDK NIH HHS R01 DK099345
6 · The paper itself

Abstract

The metabolic status of the kidney is a determinant of injury susceptibility and a measure of progression for many disease processes; however, noninvasive modalities to assess kidney metabolism are lacking. In this study, we employed positron emission tomography (PET) and intravital multiphoton microscopy (MPM) to assess cortical and proximal tubule glucose tracer uptake, respectively, following experimental perturbations of kidney metabolism. Applying dynamic image acquisition PET with 2-

Indexed as

AnimalsDeoxyglucoseFluorine RadioisotopesGlucoseKidneyMaleMiceMicroscopy, Fluorescence, MultiphotonPositron-Emission TomographyRatsRats, Sprague-DawleyDeoxyglucoseFluorine RadioisotopesGlucosekidneymultiphoton microscopyp53positron emission tomography

Identifiers

PMID26764206
PMCPMC4835928
OpenAlexW2233327579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.