Evidence map›Paper›PMID 26764019›Full record

ReviewAngewandte Chemie (International ed. in English)2016

Catalytic Enantioselective Functionalization of Unactivated Terminal Alkenes.

John R Coombs, James P Morken

Abstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. General Alkene 1,2-Journal of the American Chemical Society · 2024
    Article
  11. Article
  12. Dienes as Versatile Substrates for Transition Metal-Catalyzed Reactions.Angewandte Chemie (International ed. in English) · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Catalytic, Regioselective 1,4-Fluorodifunctionalization of Dienes.Angewandte Chemie (International ed. in English) · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

John R CoombsDepartment of Chemistry, Boston College, Merkert Research Labs, 2609 Beacon St., Chesnut Hill, MA, 02467, USA.
James P MorkenDepartment of Chemistry, Boston College, Merkert Research Labs, 2609 Beacon St., Chesnut Hill, MA, 02467, USA. morken@bc.edu.

Funding

DEVELOPMENT AND STUDY OF ENZYME FUNCTIONAL MIMICSR01GM059417 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MORKEN, JAMES PATRICK · 1999 to 2017
$4.1M
Development of Catalytic Conjunctive Coupling ReactionsR01GM118641 · NIGMS · BOSTON COLLEGE · PI MORKEN, JAMES PATRICK · 2017 to 2018
$635k
NIGMS NIH HHS R01 GM059417NIGMS NIH HHS R01 GM118641
6 · The paper itself

Abstract

Terminal alkenes are readily available functional groups which appear in α-olefins produced by the chemical industry, and they appear in the products of many contemporary synthetic reactions. While the organic transformations that apply to alkenes are amongst the most studied reactions in all of chemical synthesis, the number of reactions that apply to nonactivated terminal alkenes in a catalytic enantioselective fashion is small in number. This Minireview highlights the cases where stereocontrol in catalytic reactions of 1-alkenes is high enough to be useful for asymmetric synthesis.

Indexed as

AlkenesCatalysisStereoisomerismAlkenesalkenesasymmetric synthesischiralityenantioselective catalysistransition metals

Identifiers

PMID26764019
PMCPMC4913282

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.