ArticleHypertension research : official journal of the Japanese Society of Hypertension2016
Association of body composition and blood pressure categories with retinal vessel diameters in primary school children.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Development and validation of an Outdoor Environmental Heat Index (OETI) based on geographical, environmental and meteorological data.Scientific reports · 2026Article
- The association between retinal artery to vein ratio and fat distribution: a population-based cross-sectional study.BMC ophthalmology · 2025Article
- Development of the outdoor personal thermal index (OPTI) for evaluating heat strain risk using personal, observational, geographical, and meteorological data.BMC public health · 2025Article
- Vascular biomarkers in the prevention of childhood cardiovascular risk: From concept to clinical implementation.Frontiers in cardiovascular medicine · 2022Review
- Association of Parental Socioeconomic Status and Physical Activity with Development of Arterial Stiffness in Prepubertal Children.International journal of environmental research and public health · 2021Article
- Independent and Synergistic Effects of High Blood Pressure and Obesity on Retinal Vasculature in Young Children: The Hong Kong Children Eye Study.Journal of the American Heart Association · 2021Article
- Characteristics of the retinal microvasculature in association with cardiovascular risk markers in children with overweight, obesity and morbid obesity.Scientific reports · 2018Article
- Childhood Fat and Lean Mass: Differing Relations to Vascular Structure and Function at Age 8 to 9 YearsArteriosclerosis, thrombosis, and vascular biology · 2018Article
- Early detection of microvascular dysfunction in hypertension: the holy grail of cardiovascular prevention and risk assessment?Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Association between blood pressure and retinal arteriolar and venular diameters in Chinese early adolescent children, and whether the association has gender difference: a cross-sectional study.BMC ophthalmology · 2018Article
- Retinal Vessel Diameters and Physical Activity in Patients With Mild to Moderate Rheumatic Disease Without Cardiovascular Comorbidities.Frontiers in physiology · 2018Article
- Relationship between cardiorespiratory fitness and blood pressure in young adults: a mediation analysis of body composition.Hypertension research : official journal of the Japanese Society of Hypertension · 2017Article
- In 6- to 8-year-old children, cardiorespiratory fitness moderates the relationship between severity of life events and health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2017Article
- Ocular Signs Related to Overweight and Arterial Hypertension in Children: A Systematic Review.The open ophthalmology journal · 2017Review
- Does Physical Fitness Buffer the Relationship between Psychosocial Stress, Retinal Vessel Diameters, and Blood Pressure among Primary Schoolchildren?BioMed research international · 2016Article
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4 authors.
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Abstract
Alterations in retinal vessel diameters have been shown to be predictive of cardiovascular risk in adults and children. The aim of our study was to examine the association of body composition and blood pressure (BP) categories with retinal vessel diameters in school children. We examined anthropometric parameters, BP and retinal arteriolar (CRAE) and venular (CRVE) diameters as well as the arteriolar-to-venular diameter ratio (AVR) in 391 children (age: 7.3, s.d. 0.4). Differences between the lowest and highest BP quartiles indicated that higher systolic and diastolic BP were associated with narrower CRAE (P<0.001 for both). Children in the highest weight quartile had narrower CRAE compared with the lowest quartile (P=0.05). In the regression analysis, systolic and diastolic BP were associated with arteriolar narrowing (-0.4 measuring units (mu) per mm Hg, 95% confidence interval: [-0.6; -0.3] and -0.6 mu per mm Hg [-0.7; -0.4], respectively; P<0.001 for both). An independent association was found for diastolic BP only. Compared with normotensives (NT; 74.4% of cohort), arteriolar narrowing was already seen in children categorized as pre-hypertensive (PHT) (11.5% of cohort), which was similar to HT children (14.1% of cohort) (NT: mean 207.2 [205.6; 208.7] mu; PHT: 201.7 [197.8; 205.7] mu; HT: 199.7 [196.2; 203.3] mu; P=0.01 for PHT vs. NT and P<0.001 for HT vs. NT in systolic BP). Our results suggest that systolic and diastolic BP are main determinants of retinal arteriolar diameters; and therefore, microvascular health in young children. Pre-hypertension seems to be associated with retinal microvascular alterations early in life.
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