SynthesisBMJ clinical evidence2016
Generalised anxiety disorder in children and adolescents.
Synthesis in BMJ clinical evidence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Neuroimaging Insights: Kava's (Nutrients · 2023Trial
- Pilot Randomized Controlled Trial of the Emotion Detectives In-Out: A Blended Version of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children.Child psychiatry and human development · 2026Article
- Bidirectional relationships between intolerance of uncertainty and generalized anxiety among adolescents: insights from cross-lagged panel network analysis.Child and adolescent psychiatry and mental health · 2025Article
- Association of sleep and generalized anxiety disorder in Korean adolescents.BMC public health · 2024Article
- Are comorbidities of poor reading related to elevated anxiety in children?Annals of dyslexia · 2024Article
- Anxiety among Adolescents and Young Adults during COVID-19 Pandemic: A Multi-Country Survey.International journal of environmental research and public health · 2022Article
- Toward Linguistic Recognition of Generalized Anxiety Disorder.Frontiers in digital health · 2022Article
- Evidence-Based Pharmacotherapy of Generalised Anxiety Disorder: Focus on Agomelatine.Advances in therapy · 2021Review
- Longitudinal association between parental-to-child-Maltreatment and self-reported Generalized Anxiety Disorder symptoms in Pakistani Adolescents.Child and adolescent psychiatry and mental health · 2021Article
- Initiation of antidepressant use among refugee and Swedish-born youth after diagnosis of a common mental disorder: findings from the REMAIN study.Social psychiatry and psychiatric epidemiology · 2021Article
- Prevalence of Worry-Induced Sleep Disturbance and Associated Factors among a National Sample of In-School Adolescents in Lebanon.Behavioral sciences (Basel, Switzerland) · 2020Article
- Anxiety related disorders in adolescents in the United Arab Emirates: a population based cross-sectional study.BMC pediatrics · 2020Article
- Do Children With Comorbid Reading and Mathematics Difficulties Experience More Internalizing Problems?Journal of learning disabilitiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionGeneralised anxiety disorder (GAD) in a child or adolescent is excessive worry and tension about everyday events that the child or adolescent cannot control and that is expressed on most days for at least 6 months, to the extent that there is distress or difficulty in performing day-to-day tasks. METHODS AND OUTCOMES: We conducted a systematic overview, aiming to answer the following clinical question: What are the effects of pharmacological treatments for generalised anxiety disorder in children and adolescents? We searched: Medline, Embase, The Cochrane Library, and other important databases up to August 2014 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review).
resultsAt this update, searching of electronic databases retrieved 949 studies. After deduplication and removal of conference abstracts, 417 records were screened for inclusion in the overview. Appraisal of titles and abstracts led to the exclusion of 310 studies and the further review of 107 full publications. Of the 107 full articles evaluated, one systematic review was added at this update. We performed a GRADE evaluation for six PICO combinations.
conclusionsIn this systematic overview, we categorised the efficacy for six interventions based on information about the effectiveness and safety of antidepressants, antipsychotics, benzodiazepines, buspirone, hydroxyzine, and pregabalin.
Indexed as
Identifiers
26763675PMC4711893What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.