Evidence map›Paper›PMID 26763625›Full record

ArticleThe Diabetes educator2016

Relationship Between Health Literacy and Unintentional and Intentional Medication Nonadherence in Medically Underserved Patients With Type 2 Diabetes.

Jessica H Fan, Sarah A Lyons, Melody S Goodman, Melvin S Blanchard, Kimberly A Kaphingst

Abstract read
In one paragraph

Article in The Diabetes educator, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jessica H FanDepartment of Surgery, Washington University School of Medicine, St. Louis, Missouri (Ms Fan, Ms Lyons, Dr Goodman, Dr Kaphingst)
Sarah A LyonsDepartment of Surgery, Washington University School of Medicine, St. Louis, Missouri (Ms Fan, Ms Lyons, Dr Goodman, Dr Kaphingst)
Melody S GoodmanDepartment of Surgery, Washington University School of Medicine, St. Louis, Missouri (Ms Fan, Ms Lyons, Dr Goodman, Dr Kaphingst)
Melvin S BlanchardDepartment of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri (Dr Blanchard).
Kimberly A KaphingstDepartment of Surgery, Washington University School of Medicine, St. Louis, Missouri (Ms Fan, Ms Lyons, Dr Goodman, Dr Kaphingst)

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
Trans-NIDDK Short-Term Training for Medical StudentsT35DK074375 · NIDDK · WASHINGTON UNIVERSITY · PI BARANSKI, THOMAS JOHN · 2006 to 2015
$891k
NCI NIH HHS P30 CA091842NCI NIH HHS P30 CA91842NIDDK NIH HHS T35 DK074375
6 · The paper itself

Abstract

purposeThe purpose of this study was to investigate the relationship between health literacy and overall medication nonadherence, unintentional nonadherence, and intentional nonadherence. Limited health literacy may be associated with worse diabetes outcomes, but the literature shows mixed results, and mechanisms remain unclear. Medication adherence is associated with diabetes outcomes and may be a mediating factor. Distinguishing between unintentional and intentional nonadherence may elucidate the relationship between health literacy and nonadherence in patients with type 2 diabetes.

methodsCross-sectional study of 208 patients with type 2 diabetes recruited from a primary care clinic in St. Louis, Missouri. Information was obtained from written questionnaire and patient medical records. Bivariate and multivariable regression were used to examine predictors of medication nonadherence.

resultsThe majority of patients in the study were low income, publicly insured, and African American, with limited health literacy and a high school/GED education or less. In multivariable models, limited health literacy was significantly associated with increased unintentional nonadherence but not intentional nonadherence.

conclusionsResults suggest differences in factors affecting intentional and unintentional nonadherence. The findings also suggest interventions are needed to decrease unintentional nonadherence among patients with type 2 diabetes and limited health literacy. Efforts to address unintentional medication nonadherence among patients with type 2 diabetes with limited health literacy may improve patient health.

Indexed as

Drug MonitoringHealth Knowledge, Attitudes, PracticeMedically Underserved AreaAdultCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleHealth LiteracyHumansHypoglycemic AgentsMaleMedication AdherenceMiddle AgedMissouriMultivariate AnalysisHypoglycemic Agents

Identifiers

PMID26763625
PMCPMC5546794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.