Evidence map›Paper›PMID 26763407›Full record

ArticleNanoscale2016

Vibrational spectroscopy and imaging for concurrent cellular trafficking of co-localized doxorubicin and deuterated phospholipid vesicles.

S K Misra, P Mukherjee, A Ohoka, A S Schwartz-Duval, S Tiwari, R Bhargava, D Pan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

S K MisraDepartments of Bioengineering and Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Carle Foundation Hospital, 502 N. Busey St., Urbana, IL 61801, USA. dipanjan@illinois.edu.
P MukherjeeDepartment of Bioengineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering, Chemistry, and Mechanical Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 1304 W. Springfield Ave, Urbana, IL 61801, USA. rxb@illinois.edu.
A OhokaDepartments of Bioengineering and Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Carle Foundation Hospital, 502 N. Busey St., Urbana, IL 61801, USA. dipanjan@illinois.edu.
A S Schwartz-DuvalDepartments of Bioengineering and Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Carle Foundation Hospital, 502 N. Busey St., Urbana, IL 61801, USA. dipanjan@illinois.edu.
S TiwariDepartment of Bioengineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering, Chemistry, and Mechanical Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 1304 W. Springfield Ave, Urbana, IL 61801, USA. rxb@illinois.edu.
R BhargavaDepartment of Bioengineering, Electrical and Computer Engineering, Chemical and Biomolecular Engineering, Chemistry, and Mechanical Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, 1304 W. Springfield Ave, Urbana, IL 61801, USA. rxb@illinois.edu.
D PanDepartments of Bioengineering and Materials Science and Engineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Carle Foundation Hospital, 502 N. Busey St., Urbana, IL 61801, USA. dipanjan@illinois.edu.
Carle Foundation Hospital · USUniversity of Illinois Urbana-Champaign · USUrbana University · US

Funding

(PQC4) Towards In Vivo, 3D Cytotyping By Stimulated Raman Spectroscopic Imaging-BaR21CA190120 · NCI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT · 2014 to 2015
$374k
NCI NIH HHS R21 CA190120NCI NIH HHS R21CA190120
6 · The paper itself

Abstract

Simultaneous tracking of nanoparticles and encapsulated payload is of great importance and visualizing their activity is arduous. Here we use vibrational spectroscopy to study the in vitro tracking of co-localized lipid nanoparticles and encapsulated drug employing a model system derived from doxorubicin-encapsulated deuterated phospholipid (dodecyl phosphocholine-d38) single tailed phospholipid vesicles.

Indexed as

Antibiotics, AntineoplasticCell Line, TumorCell SurvivalDeuteriumDoxorubicinHumansMCF-7 CellsMicroscopy, Atomic ForceMicroscopy, Electron, TransmissionNanoparticlesPhosphorylcholineSpectrum Analysis, RamanX-Ray DiffractionAntibiotics, AntineoplasticDeuteriumdodecylphosphocholineDoxorubicinPhosphorylcholine

Identifiers

PMID26763407
PMCPMC4868062
OpenAlexW2227129481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.