ArticleInternational journal of colorectal disease2016
Improved survival of patients with colon cancer detected by screening colonoscopy.
Article in International journal of colorectal disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Mortality after colorectal cancer among survivors of childhood cancer.Journal of the National Cancer Institute · 2026Article
- GAN Inversion for Data Augmentation to Improve Colonoscopy Lesion Classification.IEEE journal of biomedical and health informatics · 2025Article
- Predictors of Colon Cancer Screening Among the Saudi Population at Primary Healthcare Settings in Riyadh.Current oncology (Toronto, Ont.) · 2025Article
- Long-term outcomes following the resection of screen-detected right-sided colon cancer.World journal of surgery · 2025Observational
- Prediction of anastomotic insufficiency based on the mucosal microbiome prior to colorectal surgery: a proof-of-principle study.Scientific reports · 2024Article
- Bias due to coarsening of time intervals in the inference for the effectiveness of colorectal cancer screening.International journal of epidemiology · 2024Article
- Barriers and facilitators to implementing a multilevel, multicomponent intervention promoting colorectal cancer screening in health centers: a qualitative study of key informant perspectives.BMC health services research · 2024Article
- Editorial: Artificial intelligence for early diagnosis of colorectal cancer.Frontiers in oncology · 2024Article
- Colonoscopic Screening and Risk of All-Cause and Colorectal Cancer Mortality in Young and Older Individuals.Cancer research and treatment · 2023Article
- Mailed fecal testing and patient navigation versus usual care to improve rates of colorectal cancer screening and follow-up colonoscopy in rural Medicaid enrollees: a cluster-randomized controlled trial.Implementation science communications · 2022Article
- [Impact of COVID-19 on elective and emergency colorectal surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Review
- Immunotherapy and Radioimmunotherapy for Desmoplastic Small Round Cell Tumor.Frontiers in oncology · 2021Review
- Colorectal cancer screening by colonoscopy and trends in disease-specific mortality: a population-based ecological study of 358 German districts.International journal of colorectal disease · 2019Article
- The gut microbiota and gastrointestinal surgery.Nature reviews. Gastroenterology & hepatology · 2017Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundScreening for colon cancer (CC) may not only reduce its occurrence but has also the potential to reduce the overall mortality. So far, there has been little evidence that detection of colon cancer by screening colonoscopy results in different survival rates compared to symptomatic patients. PATIENTS AND
methodsClinical, histological, diagnostic, and survival data of 1016 consecutive patients with CC from a prospectively expanded single-institutional database were analyzed for diagnostic, treatment, and prognostic factors. Findings were then stratified according to detection by screening colonoscopy vs. patients who became symptomatic prior to further diagnostic work-up.
results7.1 % of all patients were identified by screening colonoscopy for colon cancer. Screened patients were younger (68.2 vs. 64.8 years), had smaller T stage (p = 0.032), lower tumor stage (p = 0.009), and a tendency to less lymph node metastasis. Overall survival was superior in screened patients, and stage-specific survival showed a tendency to improved survival, which was not statistically significant. Furthermore, a higher percentage of screened patients underwent adjuvant chemotherapy (84.6 vs. 55.0 %, p = 0.032).
conclusionSurvival outcome and enrollment in a multimodal treatment was higher in screening-detected patients compared to patients diagnosed after the onset of clinical symptoms. Besides a potential occurrence of lead time bias, these findings strongly support the need for continued improvement of screening programs and the recruitment of more patients for colorectal cancer screening.
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