Evidence map›Paper›PMID 26762903›Full record

ReviewBiomedical chromatography : BMC2016

Extraction, chromatographic and mass spectrometric methods for lipid analysis.

Sumitra Pati, Ben Nie, Robert D Arnold, Brian S Cummings

Open access · greenAbstract readReview
In one paragraph

Review in Biomedical chromatography : BMC, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 114 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Recent Analytical Methodologies in Lipid Analysis.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Advances in Lipid Extraction Methods-A Review.International journal of molecular sciences · 2021
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sumitra PatiDepartment of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA, 30602, USA.
Ben NieDepartment of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, 36849, USA.
Robert D ArnoldDepartment of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, 36849, USA.
Brian S CummingsDepartment of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA, 30602, USA.
Auburn University · USUniversity of Georgia · US

Funding

Secretory Phospholipases sPLA2 and their Receptors for Delivering NanoparticlesR01EB016100 · NIBIB · AUBURN UNIVERSITY AT AUBURN · PI ARNOLD, ROBERT D · 2013 to 2016
$1.3M
NIBIB NIH HHS 1R01EB016100NIBIB NIH HHS R01 EB016100
6 · The paper itself

Abstract

Lipids make up a diverse subset of biomolecules that are responsible for mediating a variety of structural and functional properties as well as modulating cellular functions such as trafficking, regulation of membrane proteins and subcellular compartmentalization. In particular, phospholipids are the main constituents of biological membranes and play major roles in cellular processes like transmembrane signaling and structural dynamics. The chemical and structural variety of lipids makes analysis using a single experimental approach quite challenging. Research in the field relies on the use of multiple techniques to detect and quantify components of cellular lipidomes as well as determine structural features and cellular organization. Understanding these features can allow researchers to elucidate the biochemical mechanisms by which lipid-lipid and/or lipid-protein interactions take place within the conditions of study. Herein, we provide an overview of essential methods for the examination of lipids, including extraction methods, chromatographic techniques and approaches for mass spectrometric analysis.

Indexed as

LipidsChemical FractionationChromatographyMass SpectrometryLipidschromatographyextractionlipidomicsmass spectrometryphospholipids

Identifiers

PMID26762903
PMCPMC8425715
OpenAlexW2255236738

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.