ArticleBiomedical engineering online2016
Shape-based reconstruction of dynamic fluorescent yield with a level set method.
Article in Biomedical engineering online, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Parameterized level-set based pharmacokinetic fluorescence optical tomography using the regularized Gauss-Newton filter.Journal of biomedical optics · 2018Article
- Reconstruction of fluorescence molecular tomography with a cosinoidal level set method.Biomedical engineering online · 2017Article
- Anatomical image-guided fluorescence molecular tomography reconstruction using kernel method.Journal of biomedical optics · 2017Article
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Authors and funding
4 authors.
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Abstract
backgroundFluorescence molecular tomography (FMT) is an optical imaging technique that reveals biological processes within small animals through non-invasively reconstructing the distributions of fluorescent agents. The primary problem in FMT with non-stationary fluorescent yield is the increase of the unknown parameters to be reconstructed. In this paper, a method is proposed to reconstruct dynamic fluorescent yield.
methodsA shape-based reconstruction method that recovers dynamic fluorescent yield with a level set method is proposed for FMT. To reduce the number of unknown parameters, a level set function is introduced to describe the shape of target and a small number of parameters are used to describe the fluorescent yields at different time points.
resultsResults of simulations and phantom experiments demonstrate that the proposed method can recover well the dynamic fluorescent yields, shapes and locations of the target.
conclusionsThe proposed method can handle the cases with non-stationary fluorescent yields and recover the fluorescent yields at each projection angle.
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