Evidence map›Paper›PMID 26762511›Full record

ArticleMaternal and child health journal2016

Early Childhood Adversity and Pregnancy Outcomes.

Megan V Smith, Nathan Gotman, Kimberly A Yonkers

Abstract read
In one paragraph

Article in Maternal and child health journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed, 7 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 7 syntheses or guidelines pooled it, 172 citations in OpenAlex.

  1. Operationalizing psychological trauma in pregnancy: A systematic review.Psychological trauma : theory, research, practice and policy · 2026
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  15. When a Parent Is Born: An Integrated Approach to Perinatal Mental Health and Early Risk Screening.European journal of investigation in health, psychology and education · 2025
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  17. Associations of adverse childhood experiences (ACE) with pregnancy outcomes in people with cardiac disease.European journal of obstetrics, gynecology, and reproductive biology · 2025
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34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Megan V SmithDepartment of Psychiatry, Yale School of Medicine, 142 Temple Street, Suite #301, New Haven, CT, 06510, USA. megan.smith@yale.edu.
Nathan GotmanDepartment of Psychiatry, Yale School of Medicine, 142 Temple Street, Suite #301, New Haven, CT, 06510, USA.
Kimberly A YonkersDepartment of Psychiatry, Yale School of Medicine, 142 Temple Street, Suite #301, New Haven, CT, 06510, USA.
Yale University · US

Funding

Effects of Perinatal Depression on PTD and LBWR01HD045735 · NICHD · YALE UNIVERSITY · PI YONKERS, KIMBERLY A · 2004 to 2008
$4.6M
Three Strategies for Implementing Motivational Interviewing on Medical InpatientR01DA034243 · NIDA · YALE UNIVERSITY · PI MARTINO, STEVE, YONKERS, KIMBERLY A · 2012 to 2016
$3.7M
Project START: Screening to Augment Referral to TreatmentR01DA027194 · NIDA · YALE UNIVERSITY · PI MARTINO, STEVE, YONKERS, KIMBERLY A · 2010 to 2014
$3.3M
Yale BIRCWH Scholar Program on Women's Health and Addictive BehaviorsK12DA031050 · NIDA · YALE UNIVERSITY · PI MAZURE, CAROLYN M. · 2010 to 2014
$2.5M
NICHD NIH HHS R01 HD045735NIDA NIH HHS K12 DA031050NIDA NIH HHS R01 DA027194NIDA NIH HHS R01 DA034243
6 · The paper itself

Abstract

objectivesTo examine the association between adverse childhood experiences (ACEs) and pregnancy outcomes; to explore mediators of this association including psychiatric illness and health habits.

methodsExposure to ACEs was determined by the Early Trauma Inventory Self Report Short Form; psychiatric diagnoses were generated by the Composite International Diagnostic Interview administered in a cohort of 2303 pregnant women. Linear regression and structural equation modeling bootstrapping approaches tested for multiple mediators.

resultsEach additional ACE decreased birth weight by 16.33 g and decreased gestational age by 0.063. Smoking was the strongest mediator of the effect on gestational age.

conclusionsACEs have an enduring effect on maternal reproductive health, as manifested by mothers' delivery of offspring that were of reduced birth weight and shorter gestational age.

Indexed as

Life Change EventsPregnancy OutcomeAdolescentAdultChild, PreschoolCrime VictimsFemaleGestational AgeHumansMajor Depressive DisorderMassachusettsMothersPregnancyPremature BirthProspective StudiesSeverity of Illness IndexAdverse childhood experiencesMaternal mental healthPregnancy outcomesSmokingTrauma

Identifiers

PMID26762511
PMCPMC4849279
OpenAlexW2237725051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.