ArticleNanoscale research letters2016
Application of Cryopreserved Fibroblast Culture with Au Nanoparticles to Treat Burns.
Article in Nanoscale research letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 76 citations in OpenAlex.
- Diabetic Wound Healing: Mechanism and Treatment Strategies with a Special Focus on Angiogenesis.Current drug research reviews · 2026Review
- Review
- Hydrogels Containing Chitosan-Modified Gold Nanoparticles Show Significant Efficacy in Healing Diabetic Wounds Infected with Antibiotic-Resistant Bacteria.International journal of nanomedicine · 2024Article
- Wound healing strategies based on nanoparticles incorporated in hydrogel wound patches.RSC advances · 2023Review
- Mapping intellectual structure and research hotspots in the field of fibroblast-associated DFUs: a bibliometric analysis.Frontiers in endocrinology · 2023Article
- Ionic complexation improves wound healing in deep second-degree burns and reduces in-vitro ciprofloxacin cytotoxicity in fibroblasts.Scientific reports · 2022Article
- Biological Studies of New Implant Materials Based on Carbon and Polymer Carriers with Film Heterostructures Containing Noble Metals.Biomedicines · 2022Article
- Evaluating Antimicrobial Activity and Wound Healing Effect of Rod-Shaped Nanoparticles.Polymers · 2022Article
- Evaluation of the Performance of a ZnO-Nanoparticle-Coated Hydrocolloid Patch in Wound Healing.Polymers · 2022Article
- Nanomaterial-Based Therapy for Wound Healing.Nanomaterials (Basel, Switzerland) · 2022Review
- An Overview of Cellulose Derivatives-Based Dressings for Wound-Healing Management.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Phytochemical-Based Nano-Pharmacotherapeutics for Management of Burn Wound Healing.Gels (Basel, Switzerland) · 2021Review
- Nanomaterials in Wound Healing and Infection Control.Antibiotics (Basel, Switzerland) · 2021Review
- Dual-action of thermoresponsive gels containing DsiRNA-loaded gold nanoparticles for diabetic wound therapy: Characterization,Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2020Article
- Recent Advances in Nanomaterial-Based Wound-Healing Therapeutics.Pharmaceutics · 2020Review
- Ciprofloxacin-lidocaine-based hydrogel: development, characterization, and in vivo evaluation in a second-degree burn model.Drug delivery and translational research · 2018Article
- Treatment Strategies for Infected Wounds.Molecules (Basel, Switzerland) · 2018Review
- Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing.Advanced drug delivery reviews · 2018Review
- In Vitro Study of Influence of Au Nanoparticles on HT29 and SPEV Cell Lines.Nanoscale research letters · 2017Article
- An overview of the therapeutic potential of regenerative medicine in cutaneous wound healing.International wound journal · 2017Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim was to investigate a possibility of using the cryopreserved human culture of fibroblasts (CrHFC) with gold nanoparticles (AuNPs) to treat experimental burns in rats.The third-degree burns were modeled in white male rats. All the animals with burns were divided into three experimental groups: control group with no wound treatment; group 1 was composed of animals with CrHFC application; and group 2 consisted of those with CrHFC and AuNPs (6 μg/ml) application to a burn surface the next day after the injury. The CrHFC was applied to the methylcellulose gel in a dose of 5 × 10(4) of viable cells per 1 cm(2) of the burn. The animals were removed from the experiment on day 21 after the treatment.The CrHFC use alone and with AuNPs to the surface of burns stimulated the wound healing compared with the control. The effect of using CrHFC was less pronounced compared to the CrHFC application with AuNPs. It was reflected in a slower recovery of burns and moderate lymphocytic infiltration of granulation tissue. Immunofluorescent analysis emphasized that the use of CrHFC with AuNPs accelerated the skin synthetic processes and was helpful in recovering type I and III collagen content on day 21 after therapy.The results were likely related primarily to the unique structure and antimicrobial properties of AuNPs. Our experimental study of the effect of CrHFC with AuNPs application on regenerative processes in burns gives some pre-conditions to the following advanced bio- and nanotechnology developments.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.