ReviewJournal of clinical research in pediatric endocrinology2016
Sex Hormone-Binding Globulin in Children and Adolescents.
Review in Journal of clinical research in pediatric endocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 67 citations in OpenAlex.
- Effects of 8-week strength training on basal hormone levels, sex hormone binding globulin, insulin-like growth factor binding protein-3, oxidative stress markers, and IL-6 levels in adolescent athletes.Hormones (Athens, Greece) · 2025Trial
- Trial
- Phase I trial of TAK-385 in hormone treatment-naïve Japanese patients with nonmetastatic prostate cancer.Cancer medicine · 2019Trial
- Obesity, Oxidative Stress, and Inflammation in Precocious Puberty: Do All Roads Lead to the Hypothalamus?International journal of molecular sciences · 2026Review
- Paediatric proteomic signatures of cardiometabolic disease-associated traits predict adult disease outcomes.Nature metabolism · 2026Article
- A literature overview of age- and Tanner stage-specific reference intervals for sex hormones for children aged 0-18 years.Journal of molecular endocrinology · 2026Review
- Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys.Clinical endocrinology · 2025Article
- Sex Hormone-Binding Globulin and Metabolic Syndrome in Children and Adolescents: A Focus on Puberty.Metabolites · 2025Review
- Sex hormone-binding globulin is a valuable diagnostic indicator of gestational diabetes mellitus.Ghana medical journal · 2024Article
- Genetic regulation of testosterone level in overweight males from the Kazakh population and its association with hypogonadism.Journal of medicine and life · 2023Article
- A Million-Cow Genome-Wide Association Study of Three Fertility Traits in U.S. Holstein Cows.International journal of molecular sciences · 2023Article
- Genome-Wide Association Study of Age at First Calving in U.S. Holstein Cows.International journal of molecular sciences · 2023Article
- The value of luteinizing hormone basal values and sex hormone-binding globulin for early diagnosis of rapidly progressive central precocious puberty.Frontiers in endocrinology · 2023Article
- A Shifting Relationship Between Sex Hormone-Binding Globulin and Total Testosterone Across Puberty in Boys.The Journal of clinical endocrinology and metabolism · 2022Article
- High levels of FSH before puberty are associated with increased risk of metabolic syndrome during pubertal transition.Pediatric obesity · 2022Article
- A 4-hour Profile of 17-hydroxyprogesterone in Salt-wasting Congenital Adrenal Hyperplasia: Is the Serial Monitoring Strategy Worth the Effort?Journal of clinical research in pediatric endocrinology · 2022Article
- Urinary Protein Array Analysis to Identify Key Inflammatory Markers in Children with IgA Vasculitis Nephritis.Children (Basel, Switzerland) · 2022Article
- Difference of Precocious Puberty Between Before and During the COVID-19 Pandemic: A Cross-Sectional Study Among Shanghai School-Aged Girls.Frontiers in endocrinology · 2022Article
- HomozygousJournal of the Endocrine Society · 2021Article
- Sex Hormone-Binding Globulin Is Associated with Obesity and Dyslipidemia in Prepubertal Children.Children (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sex hormone-binding globulin (SHBG) is a circulating glycoprotein that transports testosterone and other steroids in the blood. Interest in SHBG has escalated in recent years because of its inverse association with obesity and insulin resistance, and because many studies have linked lower circulating levels of SHBG to metabolic syndrome, type 2 diabetes, nonalcoholic fatty liver disease, polycystic ovary syndrome, and early puberty. The purpose of this review is to summarize molecular, clinical, endocrine, and epidemiological findings to illustrate how measurement of plasma SHBG may be useful in clinical medicine in children.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.