Evidence map›Paper›PMID 26761468›Full record

Observational studyRevista Brasileira de terapia intensiva

Measurement of intracranial pressure and short-term outcomes of patients with traumatic brain injury: a propensity-matched analysis.

Cesar Biselli Ferreira, Estevão Bassi, Lucas Lucena, Hernandez Carreta, Leandro Costa Miranda, Paulo Fernando Guimarães Mazorcchi Tierno, Robson Luis Amorim, Fernando Godinho Zampieri, Luis Marcelo Sá Malbouisson

Abstract readObservational Study
In one paragraph

Observational study in Revista Brasileira de terapia intensiva. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
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  6. Intracranial pressure monitoring in the torture chambre.Revista Brasileira de terapia intensiva
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Cesar Biselli FerreiraHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Estevão BassiHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Lucas LucenaHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Hernandez CarretaHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Leandro Costa MirandaHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Paulo Fernando Guimarães Mazorcchi TiernoHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.
Robson Luis AmorimUniversidade de São Paulo, São Paulo, SP, Brazil.
Fernando Godinho ZampieriUnidade de Terapia Intensiva, Hospital Alemão Oswaldo Cruz, São Paulo, SP, Brazil.
Luis Marcelo Sá MalbouissonHospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the impact of intracranial pressure monitoring on the short-term outcomes of traumatic brain injury patients.

methodsRetrospective observational study including 299 consecutive patients admitted due to traumatic brain injury from January 2011 through July 2012 at a Level 1 trauma center in São Paulo, Brazil. Patients were categorized in two groups according to the measurement of intracranial pressure (measured intracranial pressure and non-measured intracranial pressure groups). We applied a propensity-matched analysis to adjust for possible confounders (variables contained in the Crash Score prognostic algorithm).

resultsGlobal mortality at 14 days (16%) was equal to that observed in high-income countries in the CRASH Study and was better than expected based on the CRASH calculator score (20.6%), with a standardized mortality ratio of 0.77. A total of 28 patients received intracranial pressure monitoring (measured intracranial pressure group), of whom 26 were paired in a 1:1 fashion with patients from the non-measured intracranial pressure group. There was no improvement in the measured intracranial pressure group compared to the non-measured intracranial pressure group regarding hospital mortality, 14-day mortality, or combined hospital and chronic care facility mortality. Survival up to 14 days was also similar between groups.

conclusionPatients receiving intracranial pressure monitoring tend to have more severe traumatic brain injuries. However, after adjusting for multiple confounders using propensity scoring, no benefits in terms of survival were observed among intracranial pressure-monitored patients and those managed with a systematic clinical protocol.

Indexed as

Intracranial PressureAdultBrain Injuries, TraumaticBrazilFemaleHospital MortalityHumansInjury Severity ScoreMaleMiddle AgedMonitoring, PhysiologicPropensity ScoreRetrospective StudiesSurvival RateTreatment OutcomeYoung Adult

Identifiers

PMID26761468
PMCPMC4738816

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.